SCHEMBL548356

SCHEMBL548356

CCC(O)c1ccc(C(C)(C)c2ccc(C(O)CC)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.56
ESR1 P03372 4/20 0.44
ESR2 Q92731 3/20 0.44
CYP3A4 P08684 3/20 0.44
AR P10275 3/20 0.44
SLC6A2 P23975 2/20 0.44
SLC6A3 Q01959 2/20 0.44
TSHR P16473 2/20 0.44
HPGD P15428 1/20 0.44
SLC6A4 P31645 1/20 0.44
HTR6 P50406 1/20 0.44
ESRRG P62508 1/20 0.44
HSD17B10 Q99714 1/20 0.44
RORC P51449 1/20 0.43
PDE2A O00408 1/20 0.41
PGR P06401 2/20 0.39
ALDH1A1 P00352 2/20 0.39
RIPK1 Q13546 1/20 0.38
HIF1A Q16665 3/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6055239 0.87 LMNA (0.56) LMNACYP3A4SLC6A2SLC6A3TSHR
SCHEMBL1607138 0.83 LMNA (0.75) LMNAESR1ESR2CYP3A4AR
SCHEMBL18290852 0.83 LMNA (0.52) LMNAESR1CYP3A4ARSLC6A2
SCHEMBL4417480 0.83 CYP3A4 (0.44) LMNAESR1ESR2CYP3A4AR
SCHEMBL17681908 0.82 HTT (0.50) LMNAARTSHRHPGDHSD17B10
SCHEMBL8908718 0.81 LMNA (0.54) LMNAESR1CYP3A4ARSLC6A2
SCHEMBL10073359 0.81 PDE2A (0.56) LMNAPDE2A
SCHEMBL15387995 0.81 PDE2A (0.56) LMNAPDE2A
SCHEMBL478137 0.81 PDE2A (0.56) LMNAPDE2A
SCHEMBL30133823 0.79 LMNA (0.47) LMNAESR1ESR2CYP3A4AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11852970-B2 Material for lithography, production method therefor, composition for lithography, pattern formation method, compound, resin, and method for purifying the compound or the resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-12-26 US disclosed
US-11572430-B2 Compound, resin, resist composition or radiation-sensitive composition, resist pattern formation method, method for producing amorphous film, underlayer film forming material for lithography, composition for underlayer film formation for lithography, method for forming circuit pattern, and purification method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-02-07 US disclosed
US-11243467-B2 Compound, resin, resist composition or radiation-sensitive composition, resist pattern formation method, method for producing amorphous film, underlayer film forming material for lithography, composition for underlayer film formation for lithography, method for forming circuit pattern, and purification method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2022-02-08 US disclosed
EP-3062151-B1 RESIST COMPOSITION, METHOD FOR FORMING RESIST PATTERN, POLYPHENOLIC COMPOUND FOR USE IN THE COMPOSITION, AND ALCOHOLIC COMPOUND THAT CAN BE DERIVED THEREFROM MITSUBISHI GAS CHEMICAL CO (JP) 2021-05-05 EP disclosed
EP-3141957-B1 RESIST MATERIAL, RESIST COMPOSITION, AND RESIST PATTERN FORMATION METHOD MITSUBISHI GAS CHEMICAL CO (JP) 2021-03-24 EP disclosed
EP-3279728-B1 RESIST BASE MATERIAL, RESIST COMPOSITION, AND METHOD FOR FORMING RESIST PATTERN MITSUBISHI GAS CHEMICAL CO (JP) 2021-03-17 EP disclosed
US-20200409261-A1 COMPOUND, RESIN, RESIST COMPOSITION OR RADIATION-SENSITIVE COMPOSITION, RESIST PATTERN FORMATION METHOD, METHOD FOR PRODUCING AMORPHOUS FILM, UNDERLAYER FILM FORMING MATERIAL FOR LITHOGRAPHY, COMPOSITION FOR UNDERLAYER FILM FORMATION FOR LITHOGRAPHY, METHOD FOR FORMING CIRCUIT PATTERN, AND PURIFICATION METHOD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-12-31 US disclosed
US-10816898-B2 2020-10-27 US disclosed
US-20200262787-A1 OPTICAL COMPONENT FORMING COMPOSITION AND CURED PRODUCT THEREOF MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-08-20 US disclosed
EP-3279190-B1 RESIST COMPOSITION, METHOD FOR FORMING RESIST PATTERN, AND POLYPHENOL COMPOUND USED THEREIN MITSUBISHI GAS CHEMICAL CO (JP) 2020-08-12 EP disclosed
US-20020016410-A1 THERMOPLASTIC RESIN COMPOSITION KATAYAMA MASHIRO (JP) 2002-02-07 US disclosed
US-6316579-B1 MOLDABILITY, USEFUL FOR PRODUCING A MOLDED ARTICLE HAVING A GOOD EXTERNAL APPEARANCE AND IMPACT RESISTANCE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2001-11-13 US disclosed
US-6197873-B1 AROMATIC POLYCARBONATE, AROMATIC POLYESTER, EPOXIDIZED CONJUGATED DIENE-VINYLAROMATIC BLOCK POLYMER THAT MAY BE HYDROGENATED, REACTION ACCELERATOR FOR EPOXY GROUPS DAICEL CHEMICAL INDUSTRY, LTD. (JP) 2001-03-06 US disclosed
US-6111016-A CONSISTS OF A POLYCARBONATE RESIN CONTAINING TERMINAL HYDROXY GROUP OF 1 TO 40% RELATIVE TO WHOLE TERMINALS AND A VINYL AROMATIC-DIENE CONTAINING COPOLYMER MODIFIED BY EPOXIDATION; DIMENSIONAL STABILITY, HEAT RESISTANCE, IMPACT STRENGTH DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2000-08-29 US disclosed
US-6066686-A POLYCARBONATE BLENDED WTIH RUBBER MODIFIED POLYSTYRENE CONTAINING 15 TO 25% BY WEIGHT OF RUBBER COMPONENT WITH SPECIFIC PARTICLE SIZE AND 15 TO 70% GEL CONTENT, AND AN EPOXIDIZED CO POLYMER OF VINYL AROMATIC AND CONJUGATE DIENE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2000-05-23 US disclosed
EP-0945491-A2 Resin composition and molded products DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 1999-09-29 EP disclosed
EP-0865450-B1 PROCESS FOR THE REMOVAL OF RESIDUAL SOLVENTS AND RESIDUAL MONOMERS FROM POWDERED POLYMERISATES BASF AG (DE) 1999-08-18 EP disclosed
EP-0893476-A1 Thermoplastic resin composition Daicel Chemical Industries, Ltd. (JP) 1999-01-27 EP disclosed
EP-0878506-A2 Polycarbonate composition Daicel Chemical Industries, Ltd. (JP) 1998-11-18 EP disclosed
EP-0816433-A2 Thermoplastic polycarbonate composition DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1998-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11852970-B2 Material for lithography, production method therefor, composition for lithography, pattern formation method, compound, resin, and method for purifying the compound or the resin SLC39A11, CROCC, TERB1 LMNA 772/4885ESR1 3319/4885ESR2 3628/4885
US-20200409261-A1 COMPOUND, RESIN, RESIST COMPOSITION OR RADIATION-SENSITIVE COMPOSITION, RESIST PATTERN FORMATION METHOD, METHOD FOR PRODUCING AMORPHOUS FILM, UNDERLAYER FILM FORMING MATERIAL FOR LITHOGRAPHY, COMPOSITION FOR UNDERLAYER FILM FORMATION FOR LITHOGRAPHY, METHOD FOR FORMING CIRCUIT PATTERN, AND PURIFICATION METHOD C9, C1R, RAD51 LMNA 736/4885ESR1 404/4885ESR2 596/4885
US-11572430-B2 Compound, resin, resist composition or radiation-sensitive composition, resist pattern formation method, method for producing amorphous film, underlayer film forming material for lithography, composition for underlayer film formation for lithography, method for forming circuit pattern, and purification method C9, C5, C1R LMNA 723/4885ESR1 446/4885ESR2 699/4885
US-20200262787-A1 OPTICAL COMPONENT FORMING COMPOSITION AND CURED PRODUCT THEREOF TERB1, C5, TERT LMNA 912/4885ESR1 2504/4885ESR2 2530/4885
US-11243467-B2 Compound, resin, resist composition or radiation-sensitive composition, resist pattern formation method, method for producing amorphous film, underlayer film forming material for lithography, composition for underlayer film formation for lithography, method for forming circuit pattern, and purification method C9, C5, C1R LMNA 723/4885ESR1 446/4885ESR2 699/4885
US-10816898-B2 C5, C9, H1-0 LMNA 3102/4885ESR1 711/4885ESR2 949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.