Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4423530 | 0.81 | CYP3A4 (0.45) | CYP3A4TDP1ESR1ESR2 | |
| SCHEMBL518737 | 0.71 | TDP1 (0.60) | CYP3A4TDP1ESR1ESR2 | |
| SCHEMBL3884707 | 0.66 | TDP1 (0.53) | CYP3A4TDP1ESR1ESR2 | |
| Ethane SCHEMBL10788468 | 0.66 | TDP1 (0.53) | CYP3A4TDP1ESR1ESR2 | |
| SCHEMBL25599728 | 0.66 | — | — | |
| SCHEMBL4252662 | 0.62 | TDP1 (0.92) | CYP3A4TDP1ESR1ESR2 | |
| SCHEMBL13876658 | 0.61 | TDP1 (0.47) | CYP3A4TDP1ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL11863752 | 0.60 | TDP1 (0.86) | CYP3A4TDP1ESR1ESR2 | |
| SCHEMBL101 | 0.58 | TDP1 (1.00) | CYP3A4TDP1ESR1ESR2 | |
| SCHEMBL5028587 | 0.58 | TDP1 (1.00) | CYP3A4TDP1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567534-B1 | PROCESS FOR THE SYNTHESIS OF CYCLOORGANYLPHOSPHANES AND DI(ALKALI METAL/ALKALINE EARTH METAL) OLIGOPHOSPHANEDIIDES | CIBA HOLDING INC (CH) | 2009-07-01 | — | — | EP | disclosed |
| US-7230137-B2 | Process for the synthesis of cycloorganylphosphanes and di(alkyli metal/alkaline earth metal) oligophosphanediides | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-06-12 | — | — | US | disclosed |
| US-20050283027-A1 | Process for the synthesis of cycloorganylphosphanes and di (alkyli metal/alkaline earth metal)oligophosphanediides | IGM GROUP B.V. (NL) | 2005-12-22 | — | — | US | disclosed |
| EP-1567534-A1 | PROCESS FOR THE SYNTHESIS OF CYCLOORGANYLPHOSPHANES AND DI(ALKALI METAL/ALKALINE EARTH METAL) OLIGOPHOSPHANEDIIDES | Ciba SC Holding AG (CH) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050668-A1 | PROCESS FOR THE SYNTHESIS OF CYCLOORGANYLPHOSPHANES AND DI(ALKALI METAL/ALKALINE EARTH METAL) OLIGOPHOSPHANEDIIDES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050283027-A1 | Process for the synthesis of cycloorganylphosphanes and di (alkyli metal/alkaline earth metal)oligophosphanediides | C1S, PPIP5K2, C1R | CYP3A4 1782/4885TDP1 2284/4885ESR1 4274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.