Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.80 |
| ▸ | HPGD | P15428 | 7/20 | 0.80 |
| ▸ | LMNA | P02545 | 1/20 | 0.80 |
| ▸ | MAPT | P10636 | 8/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | CNR2 | P34972 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804317 | 0.87 | ALDH1A1 (0.82) | ALDH1A1HPGDLMNAMAPTNPSR1 | |
| SCHEMBL5804319 | 0.87 | ALDH1A1 (0.82) | ALDH1A1HPGDLMNAMAPTNPSR1 | |
| SCHEMBL23413594 | 0.81 | ALDH1A1 (0.72) | ALDH1A1HPGDLMNAMAPTNPSR1 | |
| SCHEMBL27414336 | 0.81 | ALDH1A1 (0.72) | ALDH1A1HPGDLMNAMAPTNPSR1 | |
| SCHEMBL27414353 | 0.81 | ALDH1A1 (0.71) | ALDH1A1HPGDLMNAMAPTNPSR1 | |
| SCHEMBL1579548 | 0.81 | ALDH1A1 (0.72) | ALDH1A1HPGDLMNAMAPTNPSR1 | |
| SCHEMBL14875905 | 0.81 | ALDH1A1 (0.76) | ALDH1A1HPGDLMNAMAPTNPSR1 | |
| SCHEMBL3812791 | 0.81 | ALDH1A1 (0.71) | ALDH1A1HPGDLMNAMAPTNPSR1 | |
| SCHEMBL27414341 | 0.80 | ALDH1A1 (0.70) | ALDH1A1HPGDLMNAMAPTNPSR1 | |
| SCHEMBL27414551 | 0.80 | CACNA1B (0.75) | ALDH1A1HPGDLMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325948-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-12-31 | — | — | US | disclosed |
| US-20090325948-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-12-31 | — | — | US | disclosed |
| US-20090325948-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-12-31 | — | — | US | disclosed |
| WO-2008014307-A2 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | NOVARTIS AG (CH) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325948-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | FDPS, UMPS, GGPS1 | ALDH1A1 3119/4885HPGD 158/4885LMNA 2709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.