Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3096288 | 0.93 | ALDH1A1 (0.36) | SMN1; SMN2KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL3076988 | 0.93 | ALDH1A1 (0.36) | SMN1; SMN2KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL3087211 | 0.93 | ALDH1A1 (0.36) | SMN1; SMN2KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL4418058 | 0.86 | — | — | |
| SCHEMBL4424014 | 0.86 | KDM4E (0.32) | SMN1; SMN2KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL4413070 | 0.86 | KDM4E (0.32) | SMN1; SMN2KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL4418453 | 0.86 | ALDH1A1 (0.37) | SMN1; SMN2LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL4428562 | 0.86 | ALDH1A1 (0.37) | SMN1; SMN2LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL4413102 | 0.85 | — | — | |
| SCHEMBL4417749 | 0.85 | MLYCD (0.34) | SMN1; SMN2ALDH1A1HPGDNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620475-B1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | BASF SE (DE) | 2009-11-11 | — | — | EP | disclosed |
| EP-1620475-A1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004099262-A1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-11-18 | — | — | WO | disclosed |