Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4418453 | 1.00 | ALDH1A1 (0.37) | ALDH1A1HPGDSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL4417752 | 0.86 | SMN1; SMN2 (0.33) | ALDH1A1HPGDSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL3076988 | 0.85 | ALDH1A1 (0.36) | ALDH1A1HPGDSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL3087211 | 0.85 | ALDH1A1 (0.36) | ALDH1A1HPGDSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL3096288 | 0.85 | ALDH1A1 (0.36) | ALDH1A1HPGDSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL3681588 | 0.80 | TGM2 (0.50) | ALDH1A1SMN1; SMN2LMNAMAPTTGM2 | |
| SCHEMBL3671587 | 0.80 | TGM2 (0.50) | ALDH1A1SMN1; SMN2LMNAMAPTTGM2 | |
| SCHEMBL3677653 | 0.80 | TGM2 (0.50) | ALDH1A1SMN1; SMN2LMNAMAPTTGM2 | |
| SCHEMBL3679607 | 0.80 | TGM2 (0.50) | ALDH1A1SMN1; SMN2LMNAMAPTTGM2 | |
| SCHEMBL4413070 | 0.79 | KDM4E (0.32) | ALDH1A1HPGDSMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620475-B1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | BASF SE (DE) | 2009-11-11 | — | — | EP | disclosed |
| US-7462650-B2 | Trifunctional photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-12-09 | — | — | US | disclosed |
| US-20060270748-A1 | Novel trifunctional photoinitiators | IGM GROUP B.V. (NL) | 2006-11-30 | — | — | US | disclosed |
| EP-1620475-A1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004099262-A1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-11-18 | — | — | WO | disclosed |