SCHEMBL4417844

SCHEMBL4417844

NCCCC[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ LNPEP Q9UIQ6 3/20 0.59
▸ ERAP2 Q6P179 2/20 0.59
▸ NPY1R P25929 1/20 0.51
▸ NPY2R P49146 1/20 0.51
▸ NPY4R P50391 1/20 0.51
▸ ENPEP Q07075 3/20 0.50
▸ OPRM1 P35372 1/20 0.49
▸ NAALAD2 Q9Y3Q0 1/20 0.48
▸ OPRD1 P41143 5/20 0.46
▸ CCKAR P32238 3/20 0.46
▸ CCKBR P32239 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4417821 1.00 LNPEP (0.59) LNPEPERAP2NPY1RNPY2RNPY4R
SCHEMBL30090915 0.94 LNPEP (0.64) LNPEPERAP2NPY1RNPY2RNPY4R
SCHEMBL266554 0.94 NPY4R (0.54) LNPEPERAP2NPY1RNPY2RNPY4R
SCHEMBL30252225 0.94 NPY4R (0.54) LNPEPERAP2NPY1RNPY2RNPY4R
SCHEMBL266555 0.94 NPY4R (0.54) LNPEPERAP2NPY1RNPY2RNPY4R
SCHEMBL4293356 0.94 NPY4R (0.54) LNPEPERAP2NPY1RNPY2RNPY4R
SCHEMBL4293347 0.94 NPY4R (0.54) LNPEPERAP2NPY1RNPY2RNPY4R
SCHEMBL29365741 0.94 NPY4R (0.54) LNPEPERAP2NPY1RNPY2RNPY4R
SCHEMBL29948864 0.94 NPY4R (0.54) LNPEPERAP2NPY1RNPY2RNPY4R
SCHEMBL31025663 0.94 LNPEP (0.59) LNPEPERAP2NPY1RNPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2059806-A2 MODIFIED ANNEXIN PROTEINS AND METHODS FOR THEIR USE IN PLATELET STORAGE AND TRANSFUSION Alavita Pharmaceuticals, Inc. (US) 2009-05-20 — — EP disclosed
WO-2008008982-A2 MODIFIED ANNEXIN PROTEINS AND METHODS FOR THEIR USE IN PLATELET STORAGE AND TRANSFUSION ALAVITA PHARMACEUTICALS, INC. (US) 2008-01-17 — — WO disclosed
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