Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 6/20 | 0.94 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.94 |
| ▸ | MAPT | P10636 | 4/20 | 0.94 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.94 |
| ▸ | MEN1 | O00255 | 4/20 | 0.94 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.94 |
| ▸ | HPGD | P15428 | 3/20 | 0.94 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.94 |
| ▸ | RECQL | P46063 | 3/20 | 0.94 |
| ▸ | TSHR | P16473 | 3/20 | 0.94 |
| ▸ | POLB | P06746 | 2/20 | 0.94 |
| ▸ | LMNA | P02545 | 2/20 | 0.94 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.94 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.94 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.94 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.94 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.94 |
| ▸ | BCHE | P06276 | 1/20 | 0.94 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.94 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.94 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rhein SCHEMBL25253 | 0.97 | ALDH1A1 (1.00) | TTRALDH1A1MAPTTDP1MEN1 | |
| Rhein SCHEMBL29404324 | 0.97 | ALDH1A1 (1.00) | TTRALDH1A1MAPTTDP1MEN1 | |
| Rhein SCHEMBL1356821 | 0.95 | ALDH1A1 (0.97) | TTRALDH1A1MAPTTDP1MEN1 | |
| Rhein SCHEMBL1357918 | 0.95 | ALDH1A1 (0.97) | TTRALDH1A1MAPTTDP1MEN1 | |
| Rhein SCHEMBL8012677 | 0.95 | ALDH1A1 (0.97) | TTRALDH1A1MAPTTDP1MEN1 | |
| Rhein SCHEMBL23632879 | 0.95 | ALDH1A1 (0.97) | TTRALDH1A1MAPTTDP1MEN1 | |
| Rhein SCHEMBL23632868 | 0.95 | ALDH1A1 (0.97) | TTRALDH1A1MAPTTDP1MEN1 | |
| Rhein SCHEMBL23632984 | 0.95 | ALDH1A1 (0.97) | TTRALDH1A1MAPTTDP1MEN1 | |
| Rhein SCHEMBL23633120 | 0.95 | ALDH1A1 (0.97) | TTRALDH1A1MAPTTDP1MEN1 | |
| Rhein SCHEMBL526035 | 0.95 | ALDH1A1 (0.97) | TTRALDH1A1MAPTTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024037841-A1 | COMPOSITIONS FOR USE IN THE PREVENTION OR TREATMENT OF ORAL OR DENTAL DISORDERS OR DYSFUNCTIONS | UNIVERSITÄTSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITÄT MAINZ (DE) | 2024-02-22 | — | — | WO | disclosed |
| EP-4324471-A1 | COMPOSITIONS FOR USE IN THE PREVENTION OR TREATMENT OF ORAL OR DENTAL DISORDERS OR DYSFUNCTIONS | Universitätsmedizin der Johannes Gutenberg-Universität Mainz (DE) | 2024-02-21 | — | — | EP | disclosed |
| CN-114075158-B | Method for extracting and detecting content of salvianic acid A and salvianolic acid B | 西安碑林药业股份有限公司 | 2023-12-15 | — | — | CN | disclosed |
| EP-2872474-B1 | ANTHRAQUINONE ANALOGS AND METHODS OF MAKING AND USING THEREOF | UNIV GEORGIA STATE RES FOUND (US) | 2022-01-19 | — | — | EP | disclosed |
| CN-112180000-B | Method for detecting dampness-resolving and toxin-vanquishing composition | 广东一方制药有限公司 | 2021-09-10 | — | — | CN | disclosed |
| US-10857112-B2 | Small molecule inhibitors of RNA binding motif (RBM) proteins for the treatment of acute cellular injury | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2020-12-08 | — | — | US | disclosed |
| US-10544090-B2 | Anthraquinone analogs and methods of making and using thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2020-01-28 | — | — | US | disclosed |
| US-20170239200-A1 | SMALL MOLECULE INHIBITORS OF RNA BINDING MOTIF (RBM) PROTEINS FOR THE TREATMENT OF ACUTE CELLULAR INJURY | University of Pittsburgh - of the Commonwealth Sys tem of Higher Education (US) | 2017-08-24 | — | — | US | disclosed |
| US-9610266-B2 | Small molecule inhibitors of RNA binding motif (RBM) proteins for the treatment of acute cellular injury | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2017-04-04 | — | — | US | disclosed |
| US-20150203442-A1 | Anthraquinone Analogs and Methods of Making and Using Thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2015-07-23 | — | — | US | disclosed |
| US-6800615-B2 | PARASITICIDES, NEMATOCIDES | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-10-05 | — | — | US | disclosed |
| US-20040152645-A1 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-08-05 | — | — | US | disclosed |
| US-20040116361-A1 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-06-17 | — | — | US | disclosed |
| US-20040106686-A1 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-06-03 | — | — | US | disclosed |
| US-20030229032-A1 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2003-12-11 | — | — | US | disclosed |
| WO-2003089577-A2 | ANTIHELMINTHIC ANTHRAQUINONES AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2003-10-30 | — | — | WO | disclosed |
| WO-2003089576-A2 | ANTICANCER ANTHRAQUINONES AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2003-10-30 | — | — | WO | disclosed |
| EP-0938338-A1 | CARRIER COMPOSITION FOR INFLUENCING THE TIGHT JUNCTION PERMEABILITY | Ghyssaert, Joris Rosa Michael (BE) | 1999-09-01 | — | — | EP | disclosed |
| WO-1998005359-A1 | CARRIER COMPOSITION FOR INFLUENCING THE TIGHT JUNCTION PERMEABILITY | GHYSSAERT, JORIS, ROSA, MICHAEL (BE) | 1998-02-12 | — | — | WO | disclosed |
| EP-0821970-A1 | Carrier composition for influencing the tight junction permeability | Verhaeren, Edward Henri Charles (BE) | 1998-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10857112-B2 | Small molecule inhibitors of RNA binding motif (RBM) proteins for the treatment of acute cellular injury | RBM3, RBM12, RBM26 | TTR 1148/4885ALDH1A1 4091/4885MAPT 4689/4885 |
| US-20150203442-A1 | Anthraquinone Analogs and Methods of Making and Using Thereof | PCNA, KRAS, RECQL | TTR 4284/4885ALDH1A1 1562/4885MAPT 4878/4885 |
| US-20170239200-A1 | SMALL MOLECULE INHIBITORS OF RNA BINDING MOTIF (RBM) PROTEINS FOR THE TREATMENT OF ACUTE CELLULAR INJURY | RBM3, RBM12, RBM26 | TTR 1148/4885ALDH1A1 4091/4885MAPT 4689/4885 |
| US-20030229032-A1 | Antihelminthic anthraquinones and method of use thereof | HRH2, HRH3, HRH1 | TTR 4629/4885ALDH1A1 102/4885MAPT 4883/4885 |
| US-20040152645-A1 | Antihelminthic anthraquinones and method of use thereof | HRH2, HRH3, HRH1 | TTR 4629/4885ALDH1A1 102/4885MAPT 4883/4885 |
| US-10544090-B2 | Anthraquinone analogs and methods of making and using thereof | PCNA, KRAS, RECQL | TTR 4284/4885ALDH1A1 1562/4885MAPT 4878/4885 |
| US-20040106686-A1 | Antihelminthic anthraquinones and method of use thereof | HRH2, HRH3, HRH1 | TTR 4629/4885ALDH1A1 102/4885MAPT 4883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.