SCHEMBL4417980

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4422631	0.87	MTOR (0.46)	HTTNPC1RAB9AMAPTL3MBTL1
	SCHEMBL4417835	0.86	FAAH (0.49)	HTTNPC1RAB9AMAPTL3MBTL1
	SCHEMBL4422626	0.85	HTT (0.48)	HTTNPC1RAB9AMAPTL3MBTL1
	SCHEMBL4423905	0.85	HTT (0.60)	HTTNPC1RAB9AMAPTL3MBTL1
	SCHEMBL4417580	0.83	HTT (0.52)	HTTNPC1RAB9AMAPTL3MBTL1
	SCHEMBL2180733	0.83	NPC1 (0.50)	HTTNPC1RAB9AMAPTL3MBTL1
	SCHEMBL4430237	0.83	FAAH (0.51)	HTTNPC1RAB9AMAPTL3MBTL1
	SCHEMBL4417982	0.83	HTT (0.41)	HTTNPC1RAB9AMAPTL3MBTL1
	SCHEMBL4415454	0.83	HTT (0.48)	HTTNPC1RAB9AMAPTL3MBTL1
	SCHEMBL4412368	0.83	MAPT (0.53)	HTTNPC1RAB9AMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.