Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630878 | 0.81 | — | — | |
| SCHEMBL1547450 | 0.78 | — | — | |
| SCHEMBL1547816 | 0.78 | — | — | |
| SCHEMBL1547384 | 0.78 | — | — | |
| SCHEMBL3884382 | 0.78 | — | — | |
| SCHEMBL7048511 | 0.74 | ALDH1A1 (0.36) | LMNAGAARAB9AKDM4EMEN1 | |
| SCHEMBL9196551 | 0.74 | MAPT (0.46) | NPC1LMNAGAARAB9AL3MBTL1 | |
| SCHEMBL7053823 | 0.74 | SIGMAR1 (0.46) | GAAL3MBTL1MAPTTSHRCYP2C9 | |
| SCHEMBL6541022 | 0.74 | CASP3 (0.48) | MEN1KMT2ASMN1; SMN2ALDH1A1CYP2A6 | |
| SCHEMBL1575877 | 0.74 | CA1 (0.57) | NPC1LMNAGAARAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069240-A2 | BOOTSTRAP SYNTHESIS OF BORANES | Los Alamos National Security, LLC (US) | 2009-06-17 | — | — | EP | claimed |
| US-20080175781-A1 | Bootstrap synthesis of boranes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-07-24 | — | — | US | claimed |
| WO-2008039312-A2 | BOOTSTRAP SYNTHESIS OF BORANES | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2008-04-03 | — | — | WO | claimed |
| EP-2069240-A2 | BOOTSTRAP SYNTHESIS OF BORANES | Los Alamos National Security, LLC (US) | 2009-06-17 | — | — | EP | disclosed |
| US-20080175781-A1 | Bootstrap synthesis of boranes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-07-24 | — | — | US | disclosed |
| WO-2008039312-A2 | BOOTSTRAP SYNTHESIS OF BORANES | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2008-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080175781-A1 | Bootstrap synthesis of boranes | BCL2L13, BCL2L11, BCL2L2 | NPC1 3812/4885LMNA 1207/4885GAA 4572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.