Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RPS6KA2 | Q15349 | 4/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332204 | 0.76 | NAMPT (0.49) | NPC1RAB9ARPS6KA2RPS6KA3 | |
| SCHEMBL14003304 | 0.75 | BACE1 (0.37) | MEN1KMT2ARPS6KA2RPS6KA3 | |
| SCHEMBL5455808 | 0.75 | NAMPT (0.48) | RPS6KA2RPS6KA3 | |
| SCHEMBL12307514 | 0.74 | RPS6KA2 (0.35) | RPS6KA2RPS6KA3 | |
| SCHEMBL5334047 | 0.74 | RPS6KA2 (0.35) | RPS6KA2RPS6KA3 | |
| SCHEMBL1841985 | 0.74 | KDM4E (0.44) | NPC1RAB9AKMT2A | |
| SCHEMBL30125600 | 0.73 | CSNK1D (0.45) | NPC1RAB9A | |
| SCHEMBL3985721 | 0.73 | RAB9A (0.50) | NPC1RAB9A | |
| SCHEMBL7502655 | 0.73 | EGFR (0.50) | — | |
| SCHEMBL29129120 | 0.72 | ADORA3 (0.41) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060215-A1 | POLYAMIDES | SPIROGEN LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |