Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | SI | P14410 | 3/20 | 0.59 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.59 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.51 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4414586 | 0.79 | HSD17B10 (0.44) | MGAMGAASIMGAM2CA12 | |
| SCHEMBL4419209 | 0.79 | MGAM (0.53) | MGAMGAASIMGAM2CA12 | |
| SCHEMBL10752099 | 0.78 | MGAM (0.66) | MGAMGAASIMGAM2CSNK2A2 | |
| SCHEMBL4422879 | 0.77 | CA1 (0.51) | CA12CA2CA9CA1MEN1 | |
| SCHEMBL848452 | 0.75 | CA1 (0.66) | GAAAPPMMP2MMP9MMP8 | |
| SCHEMBL13723187 | 0.74 | GAA (0.66) | MGAMGAASIMGAM2CSNK2A2 | |
| SCHEMBL968285 | 0.74 | MGAM (0.66) | MGAMGAASIMGAM2CSNK2A2 | |
| SCHEMBL368641 | 0.74 | MGAM (1.00) | MGAMGAASIMGAM2CSNK2A2 | |
| SCHEMBL4552023 | 0.74 | MGAM (0.61) | MGAMGAASIMGAM2CA12 | |
| SCHEMBL17673 | 0.72 | CA2 (0.61) | MMP2MMP9MMP8MMP13CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1829714-B | Pna monomer and precursor | PANAGENE INC | 2012-05-30 | — | — | CN | disclosed |
| EP-1651642-B1 | PNA MONOMER AND PRECURSOR | PANAGENE INC (KR) | 2009-11-04 | — | — | EP | disclosed |
| US-7211668-B2 | PNA monomer and precursor | PANAGENE, INC. (KR) | 2007-05-01 | — | — | US | disclosed |
| EP-1651642-A4 | PNA MONOMER AND PRECURSOR | PANAGENE INC (KR) | 2006-11-29 | — | — | EP | disclosed |
| CN-1829714-A | PNA monomer and precursor | PANAGENE INC (KR) | 2006-09-06 | — | — | CN | disclosed |
| EP-1651642-A1 | PNA MONOMER AND PRECURSOR | Panagene Inc. (KR) | 2006-05-03 | — | — | EP | disclosed |
| US-20050026930-A1 | PNA monomer and precursor | PANAGENE, INC. (KR) | 2005-02-03 | — | — | US | disclosed |
| WO-2005009998-A1 | PNA MONOMER AND PRECURSOR | PANAGENE INC. (US) | 2005-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026930-A1 | PNA monomer and precursor | RNGTT, POLL, NSUN3 | MGAM 4533/4885GAA 4113/4885SI 3591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.