Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | MLYCD | O95822 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4427943 | 0.86 | GABRB1 (0.48) | RAB9ANPC1OPRK1OPRD1MMP8 | |
| SCHEMBL4416154 | 0.81 | ALDH1A1 (0.39) | RAB9AMLYCDSMN1; SMN2OPRD1CYP3A4 | |
| SCHEMBL4428582 | 0.80 | OPRD1 (0.40) | RAB9AMLYCDOPRD1CYP1A2CYP3A4 | |
| SCHEMBL4418000 | 0.79 | ALDH1A1 (0.50) | RAB9AMLYCDMAPTOPRD1CYP3A4 | |
| SCHEMBL4413080 | 0.79 | ALDH1A1 (0.46) | MLYCDSMN1; SMN2MAPTOPRD1POLB | |
| SCHEMBL4413140 | 0.78 | OPRD1 (0.43) | MLYCDOPRD1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4418619 | 0.78 | OPRD1 (0.36) | RAB9AMLYCDSMN1; SMN2OPRD1CYP1A2 | |
| SCHEMBL4418809 | 0.78 | ALDH1A1 (0.40) | RAB9AMLYCDSMN1; SMN2MAPTOPRD1 | |
| SCHEMBL4422471 | 0.78 | OPRD1 (0.39) | RAB9AMLYCDMAPTOPRD1CYP3A4 | |
| SCHEMBL4424497 | 0.78 | ALDH1A1 (0.46) | RAB9AMLYCDMAPTOPRD1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620475-B1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | BASF SE (DE) | 2009-11-11 | — | — | EP | disclosed |
| US-7462650-B2 | Trifunctional photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-12-09 | — | — | US | disclosed |
| US-20060270748-A1 | Novel trifunctional photoinitiators | IGM GROUP B.V. (NL) | 2006-11-30 | — | — | US | disclosed |
| EP-1620475-A1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004099262-A1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-11-18 | — | — | WO | disclosed |