Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4306829 | 0.81 | TDP1 (0.35) | TDP1 | |
| SCHEMBL7549527 | 0.80 | TSHR (0.43) | OPRM1OPRD1OPRK1TSHR | |
| SCHEMBL20656 | 0.80 | TSHR (0.43) | OPRM1OPRD1OPRK1TSHR | |
| SCHEMBL22105 | 0.80 | — | — | |
| SCHEMBL14917540 | 0.78 | — | — | |
| SCHEMBL428797 | 0.78 | KDM4E (0.37) | TDP1TSHR | |
| SCHEMBL10583240 | 0.78 | PAOX (0.33) | TDP1OPRM1OPRD1OPRK1 | |
| SCHEMBL9699428 | 0.78 | TDP1 (0.33) | TDP1OPRM1OPRD1OPRK1 | |
| SCHEMBL4314761 | 0.78 | PAOX (0.33) | TDP1 | |
| Methane SCHEMBL23927285 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112521532-B | Vinyl alcohol polymer and use thereof | 株式会社可乐丽 | 2023-06-13 | — | — | CN | claimed |
| US-7638524-B2 | For reducing serum cholesterol in a mammal | GENZYME CORPORATION (US) | 2009-12-29 | — | — | US | disclosed |
| US-20020155091-A1 | Combination therapy for treating hypercholesterolemia | GELTEX PHARMACEUTICALS, INC. | 2002-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020155091-A1 | Combination therapy for treating hypercholesterolemia | PCSK9, SLC10A1, NR1H4 | TDP1 3625/4885OPRM1 4177/4885OPRD1 3581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.