Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1023836 | 0.85 | CA2 (0.60) | CYP2D6SLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL8828295 | 0.85 | CA2 (0.60) | CYP2D6SLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL30559576 | 0.85 | CA2 (0.60) | CYP2D6SLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL1026086 | 0.85 | CA2 (0.60) | CYP2D6SLC6A2SLC6A4SLC6A3TAAR1 | |
| Hydrochloric Acid SCHEMBL23524379 | 0.83 | CA2 (0.58) | CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8180097 | 0.83 | FOS (0.50) | — | |
| SCHEMBL14017741 | 0.81 | TAAR1 (0.52) | CYP2D6SLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL3900627 | 0.81 | FOS (0.71) | TAAR1 | |
| SCHEMBL3900634 | 0.81 | FOS (0.71) | TAAR1 | |
| SCHEMBL27853740 | 0.80 | FOS (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114873-A2 | LIGANDS FOR IMAGING CARDIAC INNERVATION | Lantheus Medical Imaging, Inc. (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008083056-A2 | LIGANDS FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING, INC. (US) | 2008-07-10 | — | — | WO | disclosed |