Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | LDHA | P00338 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30559576 | 1.00 | CA2 (0.60) | CA2LDHAALOX15ALOX12POLB | |
| SCHEMBL1023836 | 1.00 | CA2 (0.60) | CA2LDHAALOX15ALOX12POLB | |
| SCHEMBL8828295 | 1.00 | CA2 (0.60) | CA2LDHAALOX15ALOX12POLB | |
| Hydrochloric Acid SCHEMBL23524379 | 0.98 | CA2 (0.58) | CA2LDHAALOX15ALOX12POLB | |
| SCHEMBL15624585 | 0.85 | SIGMAR1 (0.46) | CA2LDHAALOX15ALOX12POLB | |
| SCHEMBL5277808 | 0.85 | ALOX15 (0.71) | ALOX15ALOX12MEN1KMT2A | |
| SCHEMBL3900627 | 0.85 | FOS (0.71) | ALOX15ALOX12ATMTAAR1 | |
| SCHEMBL4419063 | 0.85 | CYP2D6 (0.45) | CYP2D6SLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL3900634 | 0.85 | FOS (0.71) | ALOX15ALOX12ATMTAAR1 | |
| SCHEMBL5277797 | 0.85 | ALOX15 (0.71) | ALOX15ALOX12MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000915-A1 | ISOFORM-SELECTIVE HCN BLOCKERS | UNIVERSITA' DEGLI STUDI DI FIRENZE (IT) | 2011-01-06 | — | — | WO | disclosed |