Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535657 | 1.00 | GABRA1 (0.41) | GABRA1GABRB2CYP3A4SLC6A2KCNH2 | |
| SCHEMBL1741996 | 1.00 | GABRA1 (0.41) | GABRA1GABRB2CYP3A4SLC6A2KCNH2 | |
| SCHEMBL11606150 | 0.81 | CYP3A4 (0.44) | GABRA1GABRB2CYP3A4SLC6A2KCNH2 | |
| SCHEMBL29528605 | 0.81 | CYP3A4 (0.42) | GABRA1GABRB2CYP3A4SLC6A2KCNH2 | |
| SCHEMBL251913 | 0.81 | CYP3A4 (0.42) | GABRA1GABRB2CYP3A4SLC6A2KCNH2 | |
| SCHEMBL251914 | 0.81 | CYP3A4 (0.42) | GABRA1GABRB2CYP3A4SLC6A2KCNH2 | |
| SCHEMBL253024 | 0.81 | CYP3A4 (0.42) | GABRA1GABRB2CYP3A4SLC6A2KCNH2 | |
| SCHEMBL253023 | 0.81 | CYP3A4 (0.42) | GABRA1GABRB2CYP3A4SLC6A2KCNH2 | |
| SCHEMBL28449368 | 0.81 | GABRA1 (0.39) | GABRA1GABRB2CYP3A4SLC6A2HTR2C | |
| SCHEMBL29528763 | 0.81 | CYP3A4 (0.42) | GABRA1GABRB2CYP3A4SLC6A2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0076721-A1 | Process for the carbonylation of secondary benzyl halides | Montedison S.p.A. (IT) | 1983-04-13 | — | — | EP | claimed |
| US-11731116-B2 | Manganese based complexes and uses thereof for homogeneous catalysis | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-08-22 | — | — | US | disclosed |
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-111517902-B | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2022-06-14 | — | — | CN | disclosed |
| EP-3845533-A1 | OPTICALLY ACTIVE AZABICYCLIC DERIVATIVE | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2021-07-07 | — | — | EP | disclosed |
| CN-109134267-B | Synthetic method of aromatic amine compound | 北京大学 | 2020-11-17 | — | — | CN | disclosed |
| US-10787432-B2 | N-[(pyridyloxy)propanyl]benzamides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-09-29 | — | — | US | disclosed |
| CN-111517902-A | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2020-08-11 | — | — | CN | disclosed |
| EP-3442958-B1 | NOVEL N-[(PYRIDYLOXY)PROPANYL]BENZAMIDES | BOEHRINGER INGELHEIM INT (DE) | 2020-05-06 | — | — | EP | disclosed |
| CN-109134267-A | A kind of synthetic method of aromatic amine compounds | 北京大学 | 2019-01-04 | — | — | CN | disclosed |
| EP-0977548-B2 | FRAGRANCE PRO-ACCORDS | PROCTER & GAMBLE (US) | 2008-03-26 | — | — | EP | disclosed |
| US-20080038659-A1 | Antireflective composition for photoresists | MERCK PATENT GMBH (DE) | 2008-02-14 | — | — | US | disclosed |
| EP-1859035-A1 | IMMOBILISED ENZYMES | Agency for Science, Technology and Research (SG) | 2007-11-28 | — | — | EP | disclosed |
| CN-101014565-A | Diarylsulfones as 5-HT2a antagonists | MERCK SHARP & DOHME (GB) | 2007-08-08 | — | — | CN | disclosed |
| WO-2006096132-A1 | IMMOBILISED ENZYMES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2006-09-14 | — | — | WO | disclosed |
| EP-0977548-B1 | FRAGRANCE PRO-ACCORDS | PROCTER & GAMBLE (US) | 2004-08-18 | — | — | EP | disclosed |
| US-6486330-B1 | 4-oxatricyclo[4.3.1.1 3,8]undecan-5-one derivative and process for producing the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-11-26 | — | — | US | disclosed |
| US-20020051931-A1 | Substrate having component layer that contains porous particles; surface can be made hydrophilic at low cost by coating; plate life | KONICA CORPORATION, A CORPORATION OF JAPAN (JP) | 2002-05-02 | — | — | US | disclosed |
| WO-1999020659-A1 | END-FUNCTIONALIZED POLYMERS BY CONTROLLED FREE-RADICAL POLYMERIZATION PROCESS AND POLYMERS MADE THEREFROM | THE B.F. GOODRICH COMPANY (US) | 1999-04-29 | — | — | WO | disclosed |
| EP-0196484-B1 | PRESSURE SENSITIVE MANIFOLD SHEET | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1990-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787432-B2 | N-[(pyridyloxy)propanyl]benzamides | HCRTR1, HCRTR2, CNR1 | GABRA1 92/4885GABRB2 116/4885CYP3A4 475/4885 |
| US-11731116-B2 | Manganese based complexes and uses thereof for homogeneous catalysis | ADH1C, OTC, ADH5 | GABRA1 3320/4885GABRB2 2902/4885CYP3A4 2002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.