SCHEMBL441977

SCHEMBL441977

NC(CC(=O)O)c1cn([C@H]2O[C@@H](CO)C(O)C2O)c(=S)[nH]c1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PYGM P11217 3/20 0.48
SLC28A1 O00337 1/20 0.43
SLC28A2 O43868 1/20 0.43
SLC29A1 Q99808 1/20 0.43
SLC28A3 Q9HAS3 1/20 0.43
TK2 O00142 2/20 0.43
P2RY2 P41231 1/20 0.43
CDK1 P06493 1/20 0.40
HPGD P15428 1/20 0.39
LMNA P02545 2/20 0.39
MTOR P42345 2/20 0.39
THRB P10828 1/20 0.39
MDM2 Q00987 1/20 0.39
NCOA1 Q15788 1/20 0.39
NCOA3 Q9Y6Q9 1/20 0.39
GMNN O75496 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
NFKB1 P19838 1/20 0.39
DNMT1 P26358 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20534354 1.00 PYGM (0.48) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL21570800 0.88 PYGM (0.46) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL27760732 0.86 PYGM (0.51) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL28344680 0.85 PYGM (0.50) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL27618439 0.85 PYGM (0.46) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL1067013 0.85 PYGM (0.52) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL21458099 0.85 PYGM (0.52) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL29002253 0.83 PYGM (0.46) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL5145484 0.82 PYGM (0.49) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL27965304 0.82 PYGM (0.49) PYGMSLC28A1SLC28A2SLC29A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118161602-A RNA for treating autoimmune diseases 生物技术公司 2024-06-11 CN claimed
CN-113396219-B Purification of mRNA by tangential flow filtration ETHRIS GMBH (DE) 2026-05-26 CN disclosed
CN-122070366-A Cyclic RNA compositions and methods 欧纳医疗公司 2026-05-19 CN disclosed
CN-122029278-A Constructs, methods and uses for the preparation of circular RNAs 上海环码生物医药有限公司 2026-05-12 CN disclosed
CN-120202302-A CTLA4 bi-allelic knockout 埃门多生物公司 2025-06-24 CN disclosed
CN-120158444-A Negative selection method and system for purifying circular nucleic acid 上海环码生物医药有限公司 2025-06-17 CN disclosed
CN-120153078-A RNA molecules encoding RSV-F and vaccines containing the same 辉瑞大药厂 2025-06-13 CN disclosed
CN-120153081-A APLP2 safe harbor site knock-in strategy 埃门多生物公司 2025-06-13 CN disclosed
CN-120129532-A Stabilized lipid or lipid nanoparticle suspensions 埃泽瑞斯公司 2025-06-10 CN disclosed
CN-120129688-A Efficient method for preparing highly purified 5' -capped oligonucleotides 垂林克生物技术有限公司 2025-06-10 CN disclosed
EP-1092038-A4 OCT1p, A PROTEIN HAVING HOMOLOGY TO THE ORGANIC AND SUGAR TRANSPORTER FAMILY OF PROTEINS, AND USES THEREOF MILLENNIUM PHARM INC (US) 2003-04-02 EP disclosed
US-20030027999-A1 Nucleotide sequences coding polypeptide for use in the treatment of muscula, immunological, cancer, autoimmune and respiratory disorders HUMAN GENOME SCIENCES, INC. 2003-02-06 US disclosed
WO-2001079467-A2 IDENTIFICATION OF A RENAL NADPH OXIDASE THE UNITED STATES OF AMERICA, AS REPRESENTED BY SECRETARY OF THE DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2001-10-25 WO disclosed
EP-1092038-A1 OCT1p, A PROTEIN HAVING HOMOLOGY TO THE ORGANIC AND SUGAR TRANSPORTER FAMILY OF PROTEINS, AND USES THEREOF Millennium Pharmaceuticals, Inc. (US) 2001-04-18 EP disclosed
WO-1999067415-A9 NOVEL MOLECULES OF THE T110-RELATED PROTEIN FAMILY AND USES THEREOF MILLENNIUM BIOTHERAPEUTICS INC (US) 2000-06-29 WO disclosed
WO-2000000633-A1 OCT1p, A PROTEIN HAVING HOMOLOGY TO THE ORGANIC AND SUGAR TRANSPORTER FAMILY OF PROTEINS, AND USES THEREOF MILLENNIUM PHARMACEUTICALS, INC. (US) 2000-01-06 WO disclosed
EP-0506892-B1 BORONATED NUCLEOSIDES BORON BIOLOG INC (US) 1997-10-08 EP disclosed
EP-0649411-A4 BORONATED COMPOUNDS. BORON BIOLOG INC (US) 1995-07-12 EP disclosed
EP-0649411-A1 BORONATED COMPOUNDS BORON BIOLOGICALS, INC. (US) 1995-04-26 EP disclosed
US-5130302-A Antiinflammatory agents or antitumor agents BORON BILOGICALS, INC. (US) 1992-07-14 US disclosed