Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 3/20 | 0.49 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.46 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.44 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.44 |
| ▸ | TK2 | O00142 | 2/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27965304 | 1.00 | PYGM (0.49) | PYGMP2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL21458099 | 0.88 | PYGM (0.52) | PYGMP2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL6549359 | 0.85 | PYGM (0.47) | PYGMP2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL28344680 | 0.84 | PYGM (0.50) | PYGMP2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL27760732 | 0.83 | PYGM (0.51) | PYGMP2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL441977 | 0.82 | PYGM (0.48) | PYGMP2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL20534354 | 0.82 | PYGM (0.48) | PYGMP2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL1932437 | 0.82 | PYGM (0.50) | PYGMP2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL29002253 | 0.82 | PYGM (0.46) | PYGMP2RY2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL1067013 | 0.81 | PYGM (0.52) | PYGMP2RY2SLC28A1SLC28A2SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118786212-A | SARM1 expression reduction for cell therapy | 埃门多生物公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-118355348-A | Hepatitis B Virus (HBV) knockout | 埃门多生物公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-116157515-A | Double allele knockout of SARM1 | 埃门多生物公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-103275980-B | Antibody, fusion rotein and composition | UNIV RUTGERS (US) | 2015-09-09 | — | — | CN | disclosed |
| EP-2854844-A2 | COMPOSITIONS COMPRISING AN ANTI-PDGF APTAMER AND A VEGF ANTAGONIST | Ophthotech Corporation (US) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013181495-A2 | COMPOSITIONS COMPRISING AN ANTI-PDGF APTAMER AND A VEGF ANTAGONIST | OPHTHOTECH CORPORATION (US) | 2013-12-05 | — | — | WO | disclosed |
| CN-103275980-A | Antibodies, fusion protein and composition | UNIV NEW JERSEY MED | 2013-09-04 | — | — | CN | disclosed |
| CN-101511181-B | Proteins, nucleic acids encoding the same and related methods of use | UNIV NEW JERSEY MED | 2013-08-21 | — | — | CN | disclosed |
| US-20130164748-A1 | Detection of nucleic acid amplification | APPLIED BIOSYSTEMS LLC (US) | 2013-06-27 | — | — | US | disclosed |
| CN-101511181-A | Proteins, nucleic acids encoding the same and related methods of use | UNIV MEDICINE AND DENTISTRY (US) | 2009-08-19 | — | — | CN | disclosed |
| US-20070099211-A1 | Detection of nucleic acid amplification | APPLIED BIOSYSTEMS, LLC | 2007-05-03 | — | — | US | disclosed |
| US-20060121510-A1 | Multidomain polynucleotide molecular sensors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-06-08 | — | — | US | disclosed |