Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5618886 | 1.00 | ACHE (0.62) | ACHELMNATSHRHPGDGAA | |
| SCHEMBL28397519 | 0.92 | ESR1 (0.64) | ACHELMNATSHRHPGDGAA | |
| SCHEMBL5435185 | 0.87 | HPGD (0.65) | ACHELMNATSHRHPGDGAA | |
| SCHEMBL262688 | 0.87 | HPGD (0.65) | ACHELMNATSHRHPGDGAA | |
| SCHEMBL811982 | 0.87 | ESR1 (0.54) | LMNAHPGDESR1ALDH1A1MAPT | |
| SCHEMBL6626629 | 0.85 | HPGD (0.62) | ACHELMNATSHRHPGDGAA | |
| SCHEMBL15681792 | 0.82 | LTA4H (0.53) | ACHEHPGDESR1MAPTPOLB | |
| P-Cresol SCHEMBL28453798 | 0.82 | ACHE (0.72) | ACHELMNATSHRHPGDGAA | |
| P-Cresol SCHEMBL30339010 | 0.82 | ACHE (0.72) | ACHELMNATSHRHPGDGAA | |
| P-Cresol SCHEMBL30644866 | 0.82 | ACHE (0.72) | ACHELMNATSHRHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4311938-B2 | — | — | 2009-08-12 | — | — | JP | claimed |
| US-7202311-B2 | Phosphine oxide hydroxyarl mixtures with novolac resins for co-curing epoxy resins | GREAT LAKES CORPORATION (US) | 2007-04-10 | — | — | US | claimed |
| EP-1363922-B1 | NOVEL HYDROXYARYL PHOSPHINE OXIDES MIXTURE, GLYCIDYL ETHERS AND EPOXY COMPOSITIONS, COMPOSITES AND LAMINATES DERIVED THEREFROM | GREAT LAKES CHEMICAL CORP (US) | 2006-07-26 | — | — | EP | claimed |
| US-20040225080-A1 | Phosphine oxide hydroxyaryl mixtures with novolac resins for co-curing epoxy resins | GREAT LAKES CHEMICAL CORPORATION | 2004-11-11 | — | — | US | claimed |
| JP-2004533413-A | — | — | 2004-11-04 | — | — | JP | claimed |
| US-20040121990-A1 | Novel hydroxyaryl phosphine oxides, glycidyl ethers and epoxy compositions, composites and laminates derived therefrom | GREAT LAKES CHEMICAL CORPORATION | 2004-06-24 | — | — | US | claimed |
| US-6733698-B2 | Mixture of mono-, bis- and tris-(hydroxyaryl) phosphine oxides useful to make polyglycidyl ethers or in epoxy compositions | PABU SERVICES, INC. | 2004-05-11 | — | — | US | claimed |
| EP-1363922-A2 | NOVEL HYDROXYARYL PHOSPHINE OXIDES, GLYCIDYL ETHERS AND EPOXY COMPOSITIONS, COMPOSITES AND LAMINATES DERIVED THEREFROM | Pabu Services, Inc. (US) | 2003-11-26 | — | — | EP | claimed |
| US-20030148109-A1 | Phosphine oxide hydroxyaryl mixtures with novolac resins for co-curing epoxy resins | CHEMTURA CORPORATION | 2003-08-07 | — | — | US | claimed |
| US-20020168527-A1 | Novel hydroxyaryl phosphine oxides, glycidyl ethers and epoxy compositions, composites and laminates derived therefrom | GREAT LAKES CHEMICAL CORPORATION | 2002-11-14 | — | — | US | claimed |
| WO-2002066485-A2 | NOVEL HYDROXYARYL PHOSPHINE OXIDES, GLYCIDYL ETHERS AND EPOXY COMPOSITIONS, COMPOSITES AND LAMINATES DERIVED THEREFROM | PABU SERVICES, INC. (US) | 2002-08-29 | — | — | WO | claimed |
| US-7201957-B2 | Phosphine oxide hydroxyaryl mixtures with novolac resins for co-curing epoxy resins | GREAT LAKES CORPORATION (US) | 2007-04-10 | — | — | US | disclosed |
| US-7202311-B2 | Phosphine oxide hydroxyarl mixtures with novolac resins for co-curing epoxy resins | GREAT LAKES CORPORATION (US) | 2007-04-10 | — | — | US | disclosed |
| EP-1363922-B1 | NOVEL HYDROXYARYL PHOSPHINE OXIDES MIXTURE, GLYCIDYL ETHERS AND EPOXY COMPOSITIONS, COMPOSITES AND LAMINATES DERIVED THEREFROM | GREAT LAKES CHEMICAL CORP (US) | 2006-07-26 | — | — | EP | disclosed |
| US-6887950-B2 | Phosphine oxide hydroxyaryl mixtures with novolac resins for co-curing epoxy resins | PABU SERVICES, INC. (US) | 2005-05-03 | — | — | US | disclosed |
| US-20050020801-A1 | Phosphine oxide hydroxyaryl mixtures with novolac resins for co-curing epoxy resins | GREAT LAKES CHEMICAL CORPORATION | 2005-01-27 | — | — | US | disclosed |
| US-20040225080-A1 | Phosphine oxide hydroxyaryl mixtures with novolac resins for co-curing epoxy resins | GREAT LAKES CHEMICAL CORPORATION | 2004-11-11 | — | — | US | disclosed |
| US-20030148109-A1 | Phosphine oxide hydroxyaryl mixtures with novolac resins for co-curing epoxy resins | CHEMTURA CORPORATION | 2003-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040121990-A1 | Novel hydroxyaryl phosphine oxides, glycidyl ethers and epoxy compositions, composites and laminates derived therefrom | PFAS, PTPMT1, PWWP2B | ACHE 1440/4885LMNA 724/4885TSHR 4626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.