SCHEMBL441982

SCHEMBL441982

Oc1ccc(-c2cccc3c2Cc2ccccc2-3)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.51
CHEK1 O14757 3/20 0.51
ESR2 Q92731 2/20 0.46
ABL1 P00519 2/20 0.46
ABCB1 P08183 2/20 0.46
BCR P11274 2/20 0.46
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
HTR7 P34969 1/20 0.42
HTR2B P41595 1/20 0.42
MIF P14174 1/20 0.41
MMP3 P08254 1/20 0.40
BCL2L1 Q07817 1/20 0.40
ESR1 P03372 2/20 0.38
PRCP P42785 1/20 0.38
DRD2 P14416 1/20 0.38
DRD4 P21917 1/20 0.38
DRD3 P35462 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21880049 0.91 LTA4H (0.46) PNMTCHEK1ESR2ABL1ABCB1
1-Naphthol SCHEMBL17456245 0.87 CYP1A2 (0.47) PNMTCHEK1ESR2ABL1ABCB1
SCHEMBL27770268 0.86 MAOA (0.53) CHEK1ESR2ABL1ABCB1BCR
SCHEMBL28332726 0.85 CHEK1 (0.48) PNMTCHEK1ESR2ABL1ABCB1
SCHEMBL28928665 0.85 PNMT (0.50) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL29907851 0.84 CHEK1 (0.48) PNMTCHEK1ESR2ABL1ABCB1
SCHEMBL1828388 0.84 CHEK1 (0.48) PNMTCHEK1ESR2ABL1ABCB1
SCHEMBL29170221 0.84 CHEK1 (0.40) PNMTCHEK1ESR2ABL1ABCB1
SCHEMBL29809707 0.84 PNMT (0.53) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL70992 0.84 PNMT (0.53) PNMTNPC1RAB9AHTR7HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3424 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113801606-B Anisotropic conductive adhesive composition, conductive adhesive film, connector and semiconductor device 航天智造科技股份有限公司 2024-07-09 CN claimed
CN-114230779-B Polycarbonate and preparation method and application thereof 万华化学集团股份有限公司 2024-05-03 CN claimed
CN-117327265-B Preparation method of polycarbonate 上海芮澜工程科技有限公司 2024-04-16 CN claimed
CN-117801252-A Preparation process of polycarbonate 万华化学集团股份有限公司 2024-04-02 CN claimed
CN-115298270-B Method for preparing thermochromic water-based gel ink composition and thermochromic water-based gel ink composition thereof 法国比克公司 2024-03-26 CN claimed
CN-115105965-B Method for eliminating defects of hollow fiber gas separation membrane assembly 中国科学院过程工程研究所 2024-03-08 CN claimed
CN-115725063-B Polycarbonate and preparation method thereof 拓烯科技(衢州)有限公司 2024-02-23 CN claimed
CN-117510820-A Polycarbonate with heat resistance, yellowing resistance and precipitation resistance as well as preparation method and application thereof 万华化学集团股份有限公司 2024-02-06 CN claimed
CN-115232295-B Bending-resistant polyester film and preparation method thereof 新光合成纤维股份有限公司 2024-02-06 CN claimed
CN-115916929-B Use of oils comprising non-neurotoxic antiwear additives NYCO公司 2024-01-30 CN claimed
US-5516877-A Crosslinkable carbonate polymers of dihydroxyaryl fluorene THE DOW CHEMICAL COMPANY (US) 1996-05-14 US claimed
EP-0651772-A1 THIODIPHENOL COPOLYCARBONATES AND THEIR USE AS COMPONENTS OF MULTILAYERED POLYMERIC REFLECTIVE BODIES THE DOW CHEMICAL COMPANY (US) 1995-05-10 EP claimed
US-5391693-A Copolymerization of aromatic diol and 9,9-bis(4-hydroxyphenyl) fluorene derivative in presence of phosgene or derivatives in inert solvent in presence of potassium hydroxide IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1995-02-21 US claimed
US-5322528-A Reducing agent precursors TEXACO INC. (US) 1994-06-21 US claimed
WO-1994002533-A1 THIODIPHENOL COPOLYCARBONATES AND THEIR USE AS COMPONENTS OF MULTILAYERED POLYMERIC REFLECTIVE BODIES THE DOW CHEMICAL COMPANY (US) 1994-02-03 WO claimed
CN-1079675-A 2, two (4-hydroxy phenyl) the propane method for making granules of 2- NIPPON STEEL CHEMICAL CO (JP) 1993-12-22 CN claimed
EP-0400128-B1 PROCESS FOR POLYCONDENSATION OF DIPHENOLS WITH HALOGENIDES OF DICARBOXYLIC ACIDS ISONOVA TECH INNOVAT GMBH (AT) 1993-12-08 EP claimed
EP-0564233-A1 Composition of matter for high temperature phenolphthalein-, phenolphthalide-, fluorene-, xanthane-, and anthrone-S-triazines that are soluble in diesel fuel TEXACO DEVELOPMENT CORPORATION (US) 1993-10-06 EP claimed
EP-0542320-A1 Process for the preparation of an aromatic polyester MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-05-19 EP claimed
EP-0064972-B1 HIGH-MOLECULAR AROMATIC POLYESTER, PROCESS FOR PREPARING FILMS THEREFROM AND SUCH FILMS, AN ELECTRICAL CONDUCTOR WITH AN INSULATION OF THIS POLYESTER, AND PROCESS FOR MAKING SUCH AN INSULATION ISOVOLTAÖsterreichische IsolierstoffwerkeAktiengesellschaft (AT) 1988-03-16 EP claimed