Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10646082 | 0.89 | SIGMAR1 (0.55) | MAPTKDM4ESIGMAR1 | |
| SCHEMBL8117468 | 0.86 | MAPT (0.67) | MAPTKDM4ESIGMAR1 | |
| SCHEMBL24322840 | 0.85 | KCNH2 (0.59) | SIGMAR1 | |
| SCHEMBL10686392 | 0.85 | SIGMAR1 (0.60) | MAPTKDM4ESIGMAR1 | |
| SCHEMBL9096825 | 0.83 | MAPT (0.56) | MAPTKDM4ESIGMAR1 | |
| Hydrochloric Acid SCHEMBL10502749 | 0.83 | SIGMAR1 (0.59) | MAPTKDM4ESIGMAR1 | |
| SCHEMBL23751004 | 0.83 | SIGMAR1 (0.63) | MAPTKDM4ESIGMAR1 | |
| SCHEMBL24076499 | 0.82 | ALDH1A1 (0.67) | KDM4ESIGMAR1 | |
| SCHEMBL5878453 | 0.81 | PKM (0.57) | MAPTKDM4E | |
| SCHEMBL21068030 | 0.81 | MAPT (0.54) | MAPTKDM4ESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103012318-B | Fluorobenzyl substituted piperazine compound and preparation and medical application thereof | UNIV DALI | 2014-12-10 | — | — | CN | claimed |
| CN-103012318-A | Fluorobenzyl substituted piperazine compound and preparation and medical application thereof | UNIV DALI | 2013-04-03 | — | — | CN | claimed |
| EP-3796900-B1 | TRITERPENE AMINE DERIVATIVES | DFH THERAPEUTICS (US) | 2026-04-08 | — | — | EP | disclosed |
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | Psomagen Inc. (US) | 2022-04-21 | — | — | US | disclosed |
| US-11236122-B2 | Triterpene amine derivatives | DFH THERAPEUTICS (US) | 2022-02-01 | — | — | US | disclosed |
| US-11236122-B2 | Triterpene amine derivatives | DFH THERAPEUTICS (US) | 2022-02-01 | — | — | US | disclosed |
| US-20210253627-A1 | TRITERPENE AMINE DERIVATIVES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2021-08-19 | — | — | US | disclosed |
| US-20210253627-A1 | TRITERPENE AMINE DERIVATIVES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2021-08-19 | — | — | US | disclosed |
| CN-103012318-B | Fluorobenzyl substituted piperazine compound and preparation and medical application thereof | UNIV DALI | 2014-12-10 | — | — | CN | disclosed |
| CN-103012318-B | Fluorobenzyl substituted piperazine compound and preparation and medical application thereof | UNIV DALI | 2014-12-10 | — | — | CN | disclosed |
| US-8492384-B2 | Imidazolylalkylcarbonyl derivatives as calcium channel modulators and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-07-23 | — | — | US | disclosed |
| EP-0802196-B1 | Alkylenediamine derivatives as drugs for the treatment of ulcers and the inhibition of Helicobacter pylori | SHISEIDO CO LTD (JP) | 2001-08-29 | — | — | EP | disclosed |
| US-6096746-A | Indazole compound containing a monocyclic amine structure | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5945434-A | TREATMENT OF GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5814634-A | PEPTIC ULCERS, GASTRIC ULCERS | SHISEIDO CO. LTD. (JP) | 1998-09-29 | — | — | US | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0829474-A1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-03-18 | — | — | EP | disclosed |
| EP-0802196-A1 | Alkylenediamine derivative, antiulcer drug, and antibacterial drug | SHISEIDO COMPANY LIMITED (JP) | 1997-10-22 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253627-A1 | TRITERPENE AMINE DERIVATIVES | BET1, PGGT1B, NFATC1 | MAPT 1598/4885KDM4E 1661/4885SIGMAR1 1936/4885 |
| US-11236122-B2 | Triterpene amine derivatives | BET1, PGGT1B, NFATC1 | MAPT 1598/4885KDM4E 1661/4885SIGMAR1 1936/4885 |
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | HTRA1, GIPR, HPN | MAPT 4494/4885KDM4E 4426/4885SIGMAR1 3622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.