SCHEMBL4420288

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29534868	0.87	TDP1 (0.55)	TDP1PTPN1APOBEC3GTAAR1HSPA5
	SCHEMBL31203	0.87	TDP1 (0.55)	TDP1PTPN1APOBEC3GTAAR1HSPA5
	SCHEMBL132297	0.81	HSPA5 (0.38)	APOBEC3GTAAR1HSPA5TSHRCYP2D6
	SCHEMBL30563551	0.79	APOBEC3G (0.48)	TDP1PTPN1APOBEC3GTAAR1HSPA5
	SCHEMBL27891	0.79	APOBEC3G (0.48)	TDP1PTPN1APOBEC3GTAAR1HSPA5
	SCHEMBL6632824	0.79	APOBEC3G (0.48)	APOBEC3GTAAR1HSPA5CYP4F2CYP4A11
	SCHEMBL28470833	0.75	TAAR1 (0.56)	TAAR1HTR2ACYP2D6
	SCHEMBL6267374	0.75	TDP1 (0.44)	TDP1PTPN1TAAR1HTR2ATSHR
	SCHEMBL321423	0.75	ADRA2B (0.39)	TAAR1CYP4F2CYP4A11ALDH1A1
	SCHEMBL11010811	0.75	LIPG (0.32)	TAAR1CYP4F2CYP4A11HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.