Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.38 |
| ▸ | HTR2A | P28223 | 10/20 | 0.38 |
| ▸ | PIM1 | P11309 | 4/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4420502 | 0.86 | HTR2C (0.38) | HTR2CHTR2APIM1HTR7HTR6 | |
| SCHEMBL4421142 | 0.69 | ALDH1A1 (0.36) | HTR2CHTR2AHTR6KDM4EMEN1 | |
| SCHEMBL4557944 | 0.69 | KDR (0.45) | PIM1KDM4EMEN1USP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9573826 | 0.66 | HTR2C (0.65) | HTR2CHTR2AKDM4EMEN1MAPT | |
| Hydrochloric Acid SCHEMBL4591697 | 0.63 | HTR2A (0.45) | HTR2CHTR2AHTR7HTR6KDM4E | |
| SCHEMBL6294206 | 0.63 | HTR2C (0.74) | HTR2CHTR2AKDM4EMEN1MAPT | |
| Hydrochloric Acid SCHEMBL9382041 | 0.61 | PRKCA (0.63) | MEN1KMT2A | |
| SCHEMBL613000 | 0.59 | MEN1 (0.54) | HTR2CHTR2AMEN1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9573793 | 0.59 | HTR2C (0.51) | HTR2CHTR2AHTR6KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7097944 | 0.59 | HTR2C (0.51) | HTR2CHTR2AHTR6KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192147-A1 | [a]-FUSED INDOLE COMPOUNDS, THEIR USE AS mTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES | WYETH (US) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192147-A1 | [a]-FUSED INDOLE COMPOUNDS, THEIR USE AS mTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES | MTOR, RICTOR, PIK3C2A | HTR2C 826/4885HTR2A 780/4885PIM1 179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.