Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4420502 | 0.83 | HTR2C (0.38) | HTR2CHTR2AHTR2BNPC1HTR6 | |
| SCHEMBL4420499 | 0.69 | HTR2C (0.38) | ALDH1A1HTR2CHTR2AHTR6KDM4E | |
| SCHEMBL4557945 | 0.66 | CYP1A1 (0.47) | ALDH1A1PRKCAGSK3BKDM4EMEN1 | |
| SCHEMBL16201631 | 0.59 | MTNR1A (0.45) | ALDH1A1MTNR1AMTNR1BHTR2CHTR2A | |
| SCHEMBL4592565 | 0.58 | MTNR1A (0.43) | MTNR1AMTNR1BNPC1HTR6KDM4E | |
| SCHEMBL4686238 | 0.58 | KCNA5 (0.53) | ALDH1A1MTNR1AMTNR1BHTR6KDM4E | |
| Hydrochloric Acid SCHEMBL4875908 | 0.58 | MTNR1A (0.42) | ALDH1A1MTNR1AMTNR1BHTR6KDM4E | |
| SCHEMBL6979869 | 0.58 | ALDH1A1 (0.42) | ALDH1A1NPC1KDM4EMEN1USP2 | |
| SCHEMBL10730651 | 0.57 | HTR2A (0.45) | ALDH1A1HTR2CHTR2AHTR2BHTR6 | |
| SCHEMBL8447679 | 0.54 | MEN1 (0.46) | ALDH1A1NPC1KDM4EMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192147-A1 | [a]-FUSED INDOLE COMPOUNDS, THEIR USE AS mTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES | WYETH (US) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192147-A1 | [a]-FUSED INDOLE COMPOUNDS, THEIR USE AS mTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES | MTOR, RICTOR, PIK3C2A | ALDH1A1 3904/4885MTNR1A 2107/4885MTNR1B 2048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.