SCHEMBL4421020

SCHEMBL4421020

CCCCCN1CCN(C)C1=O

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 2/20 0.41
ALOX5 P09917 2/20 0.40
PTGS1 P23219 3/20 0.39
PTGS2 P35354 3/20 0.39
MGLL Q99685 3/20 0.39
FAAH O00519 2/20 0.39
CYP1A1 P04798 2/20 0.39
GNAI3 P08754 1/20 0.38
GNAO1 P09471 1/20 0.38
GNAI1 P63096 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
THRB P10828 1/20 0.38
S1PR1 P21453 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31729293 0.98 GBA1 (0.44) GBA1ALOX5PTGS1PTGS2MGLL
SCHEMBL9322926 0.98 GBA1 (0.44) GBA1ALOX5PTGS1PTGS2MGLL
SCHEMBL25752208 0.98 GBA1 (0.44) GBA1ALOX5PTGS1PTGS2MGLL
SCHEMBL10721232 0.98 GBA1 (0.44) GBA1ALOX5PTGS1PTGS2MGLL
SCHEMBL31728677 0.98 GBA1 (0.44) GBA1ALOX5PTGS1PTGS2MGLL
SCHEMBL10721244 0.98 GBA1 (0.44) GBA1ALOX5PTGS1PTGS2MGLL
SCHEMBL6561436 0.98 GBA1 (0.44) GBA1ALOX5PTGS1PTGS2MGLL
SCHEMBL25752146 0.98 GBA1 (0.44) GBA1ALOX5PTGS1PTGS2MGLL
SCHEMBL750176 0.94 MEN1 (0.41) GBA1ALOX5CYP1A1ALDH1A1GAA
SCHEMBL21808765 0.91 ALOX5 (0.41) GBA1ALOX5PTGS1PTGS2MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203087-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-06-29 US disclosed
WO-2018098204-A1 6-MEMBERED URACIL ISOSTERES CV6 THERAPEUTICS (NI) LIMITED (GB) 2018-05-31 WO disclosed
WO-2018098209-A1 AMINO SULFONYL COMPOUNDS CV6 THERAPEUTICS (NI) LIMITED (GB) 2018-05-31 WO disclosed
US-20090042762-A1 CLEANER COMPOSITION FOR REMOVAL OF LEAD-FREE SOLDERING FLUX, RINSING AGENT FOR REMOVAL OF LEAD-FREE SOLDERING FLUX, AND METHOD FOR REMOVAL OF LEAD-FREE SOLDERING FLUX ARAKAWA CHEMICAL INDUSTRIES, LTD. (JP) 2009-02-12 US disclosed
EP-1295935-B1 DETERGENT COMPOSITION ARAKAWA CHEM IND (JP) 2007-03-21 EP disclosed
US-7018964-B2 The cleaning composition of this invention comprises, as effective components, a compound (A) represented by the formula (1) and a nonionic surfactant (B): polyoxyethylene glycol phosphate ARAKAWA CHEMICAL INDUSTRIES, LTD. (JP) 2006-03-28 US disclosed
US-20030181349-A1 The cleaning composition of this invention comprises, as effective components, a compound (A) represented by the formula (1) and a nonionic surfactant (B): polyoxyethylene glycol phosphate ARAKAWA CHEMICAL INDUSTRIES, LTD. (JP) 2003-09-25 US disclosed
EP-1295935-A1 DETERGENT COMPOSITION Arakawa Chemical Industries, Ltd. (JP) 2003-03-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230203087-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF RNGTT, NSUN2, ALKBH1 GBA1 503/4885ALOX5 1815/4885PTGS1 4765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.