Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292371 | 1.00 | ESR1 (0.46) | ESR1ELANEACHESMN1; SMN2LMNA | |
| SCHEMBL28386684 | 0.98 | ELANE (0.47) | ESR1ELANEACHESMN1; SMN2LMNA | |
| SCHEMBL7288546 | 0.92 | ELANE (0.45) | ESR1ELANESMN1; SMN2LMNANPSR1 | |
| SCHEMBL5839061 | 0.92 | CHRM2 (0.44) | ESR1ACHEHTTCYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL11562136 | 0.90 | ELANE (0.44) | ESR1ELANESMN1; SMN2LMNANPSR1 | |
| SCHEMBL5838710 | 0.89 | MAPT (0.44) | ELANEACHELMNATSHRMAPK1 | |
| SCHEMBL9170859 | 0.88 | ACHE (0.43) | ESR1ACHESMN1; SMN2LMNAS1PR2 | |
| SCHEMBL11426788 | 0.85 | ABL1 (0.43) | ESR1ELANEACHESMN1; SMN2LMNA | |
| SCHEMBL5840516 | 0.85 | MAPT (0.44) | ACHELMNATSHRMAPK1HTT | |
| SCHEMBL28345017 | 0.84 | ACHE (0.41) | ESR1ELANEACHESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2583958-B1 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INST TECHNOLOGY (US) | 2016-08-10 | — | — | EP | disclosed |
| EP-2583958-B1 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INST TECHNOLOGY (US) | 2016-08-10 | — | — | EP | disclosed |
| EP-2583958-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | Massachusetts Institute of Technology (MIT) (US) | 2013-04-24 | — | — | EP | disclosed |
| EP-2583958-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | Massachusetts Institute of Technology (MIT) (US) | 2013-04-24 | — | — | EP | disclosed |
| US-7560582-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-07-14 | — | — | US | disclosed |
| US-7560582-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-07-14 | — | — | US | disclosed |
| US-7560582-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-07-14 | — | — | US | disclosed |
| US-20080033171-A1 | Ligands for Metals and Improved Metal-Catalyzed Processes Based Thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-02-07 | — | — | US | disclosed |
| US-20080033171-A1 | Ligands for Metals and Improved Metal-Catalyzed Processes Based Thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-02-07 | — | — | US | disclosed |
| US-20080033171-A1 | Ligands for Metals and Improved Metal-Catalyzed Processes Based Thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-02-07 | — | — | US | disclosed |
| US-20040171833-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | NATIONAL SCIENCE FOUNDATION | 2004-09-02 | — | — | US | disclosed |
| US-20040010149-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | NATIONAL SCIENCE FOUNDATION | 2004-01-15 | — | — | US | disclosed |
| EP-1354887-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | Massachusetts Insitute of Technology (US) | 2003-10-22 | — | — | EP | disclosed |
| US-6562989-B2 | Bicyclopentyl iron ligand and transition metal catalyst | YALE UNIVERSITY | 2003-05-13 | — | — | US | disclosed |
| US-20030008768-A1 | Catalyst for aromatic C-O, C-N, and C-C bond formation | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-01-09 | — | — | US | disclosed |
| US-20020156295-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | NATIONAL SCIENCE FOUNDATION | 2002-10-24 | — | — | US | disclosed |
| US-6395916-B1 | AMINE, PHOSPHINE LIGANDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2002-05-28 | — | — | US | disclosed |
| US-6307087-B1 | USE OF CATALYSTS COMPRISING THESE LIGANDS IN TRANSITION METAL-CATALYZED CARBON-HETEROATOM AND CARBON-CARBON BOND-FORMING REACTIONS. | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2001-10-23 | — | — | US | disclosed |
| EP-1097158-A2 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000002887-A2 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2000-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010149-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | THEM6, SOD1, SLC30A6 | ESR1 974/4885ELANE 2043/4885ACHE 1084/4885 |
| US-20080033171-A1 | Ligands for Metals and Improved Metal-Catalyzed Processes Based Thereon | THEM6, SOD1, SLC30A6 | ESR1 974/4885ELANE 2043/4885ACHE 1084/4885 |
| US-20040171833-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | THEM6, SLC30A6, SOD1 | ESR1 811/4885ELANE 1790/4885ACHE 795/4885 |
| US-20020156295-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | THEM6, SOD1, SLC30A6 | ESR1 974/4885ELANE 2043/4885ACHE 1084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.