Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4416711 | 0.93 | CNR1 (0.37) | F10KCNH2MCHR1KMT2ACCR2 | |
| SCHEMBL4413722 | 0.92 | F10 (0.35) | F10KCNH2MCHR1KMT2ACCR2 | |
| SCHEMBL4428598 | 0.92 | F10 (0.36) | F10KMT2ACCR2CCR5CNR1 | |
| SCHEMBL4417585 | 0.91 | CNR1 (0.40) | F10KMT2ACCR2CCR5CNR1 | |
| SCHEMBL4420896 | 0.91 | CCR2 (0.36) | F10KCNH2MCHR1KMT2ACCR2 | |
| SCHEMBL4417993 | 0.90 | NSD2 (0.39) | F10KMT2ACCR2CCR5CNR1 | |
| SCHEMBL4427802 | 0.90 | F10 (0.34) | F10KCNH2MCHR1KMT2ACCR2 | |
| SCHEMBL4415059 | 0.90 | CCR2 (0.35) | F10KCNH2MCHR1KMT2ACCR2 | |
| SCHEMBL5027344 | 0.89 | CCR2 (0.43) | F10KCNH2MCHR1KMT2ACCR2 | |
| SCHEMBL4426067 | 0.85 | CNR1 (0.40) | CCR2CCR5CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606255-B1 | CYCLIC DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2009-11-11 | — | — | EP | claimed |