SCHEMBL4421739

SCHEMBL4421739

C[Si](C)(C)c1ccccc1C[O]

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.37
IDO1 P14902 1/20 0.31
GABRA1 P14867 2/20 0.31
GABRB2 P47870 2/20 0.31
PNMT P11086 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12441757 0.83 GABRA1 (0.42) MGAMGABRA1GABRB2
SCHEMBL21195901 0.81 MGAM (0.37) MGAMIDO1PNMT
SCHEMBL8970526 0.76 MGAM (0.37) MGAMIDO1GABRA1GABRB2PNMT
SCHEMBL21271561 0.76 MGAM (0.37) MGAMIDO1PNMT
SCHEMBL9206225 0.76 APOBEC3G (0.48) MGAM
SCHEMBL5051116 0.76 IDO1 (0.44) MGAMIDO1PNMT
SCHEMBL4432992 0.76 TSHR (0.38) MGAMIDO1PNMT
SCHEMBL10700672 0.76 PNMT (0.50) MGAMPNMT
SCHEMBL4420821 0.76 IDO1 (0.31) IDO1
SCHEMBL13185417 0.76 MGAM (0.35) MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7482414-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-27 US disclosed