Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4848754 | 0.84 | TSHR (0.36) | TSHRALDH1A1KMT2APNMTCYP1A2 | |
| SCHEMBL15453503 | 0.79 | ALDH1A1 (0.33) | TSHRALDH1A1KMT2APNMT | |
| SCHEMBL12441757 | 0.78 | GABRA1 (0.42) | MGAMCYP2D6MAPT | |
| SCHEMBL937353 | 0.78 | ALDH1A1 (0.39) | TSHRALDH1A1KMT2APNMTIDO1 | |
| SCHEMBL9206225 | 0.76 | APOBEC3G (0.48) | TSHRMGAMKMT2A | |
| SCHEMBL21195901 | 0.76 | MGAM (0.37) | MGAMPNMTIDO1 | |
| SCHEMBL21271561 | 0.76 | MGAM (0.37) | MGAMPNMTIDO1 | |
| SCHEMBL4421739 | 0.76 | MGAM (0.37) | MGAMPNMTIDO1 | |
| SCHEMBL5051116 | 0.76 | IDO1 (0.44) | MGAMPNMTIDO1 | |
| SCHEMBL10700672 | 0.76 | PNMT (0.50) | MGAMPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190233444-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-01 | — | — | US | claimed |
| CN-104710644-B | A kind of method that antimicrobial surface is prepared on medical macromolecular materials surface | 中国科学院长春应用化学研究所 | 2017-09-22 | — | — | CN | claimed |
| CN-104710644-A | Method for preparing antibacterial surface on medical high polymer material surface | CHANGCHUN APPLIED CHEMISTRY | 2015-06-17 | — | — | CN | claimed |
| EP-3368514-B1 | TRISUBSTITUTED SILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AG (DE) | 2021-08-18 | — | — | EP | disclosed |
| US-10683311-B2 | Trisubstitutedsilylphenoxyheterocycles and analogues | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-06-16 | — | — | US | disclosed |
| US-20190233444-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-01 | — | — | US | disclosed |
| CN-104710644-B | A kind of method that antimicrobial surface is prepared on medical macromolecular materials surface | 中国科学院长春应用化学研究所 | 2017-09-22 | — | — | CN | disclosed |
| CN-104710644-A | Method for preparing antibacterial surface on medical high polymer material surface | CHANGCHUN APPLIED CHEMISTRY | 2015-06-17 | — | — | CN | disclosed |
| EP-2032624-A1 | WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION | Sabic Innovative Plastics IP B.V. (NL) | 2009-03-11 | — | — | EP | disclosed |
| WO-2008002757-A1 | WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10683311-B2 | Trisubstitutedsilylphenoxyheterocycles and analogues | PIK3C3, ERG28, DDT | TSHR 4289/4885ALDH1A1 3139/4885MGAM 250/4885 |
| US-20190233444-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | PIK3C3, ERG28, DDT | TSHR 4289/4885ALDH1A1 3139/4885MGAM 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.