Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555964 | 0.87 | TRPV4 (0.43) | ALDH1A1CYP3A4MAPK1MEN1MAPT | |
| SCHEMBL10411218 | 0.85 | TRPV4 (0.42) | ALDH1A1CYP3A4MAPK1MEN1MAPT | |
| SCHEMBL4334905 | 0.85 | ALDH1A1 (0.45) | ALDH1A1CYP3A4MAPK1MEN1MAPT | |
| SCHEMBL10941730 | 0.84 | TRPV4 (0.45) | ALDH1A1CYP3A4MAPK1MEN1MAPT | |
| SCHEMBL31038739 | 0.84 | TRPV4 (0.45) | ALDH1A1CYP3A4MAPK1MEN1MAPT | |
| SCHEMBL8119989 | 0.80 | ALDH1A1 (0.39) | ALDH1A1CYP3A4MAPK1MEN1MAPT | |
| SCHEMBL11120954 | 0.80 | TRPV4 (0.42) | ALDH1A1CYP3A4MAPK1MEN1MAPT | |
| SCHEMBL3976816 | 0.80 | L3MBTL1 (0.39) | ALDH1A1CYP3A4MAPK1MEN1MAPT | |
| SCHEMBL3561080 | 0.80 | PRKACA (0.42) | ALDH1A1CYP3A4MAPK1MEN1MAPT | |
| SCHEMBL7555568 | 0.80 | ALDH1A1 (0.39) | ALDH1A1CYP3A4MAPK1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441004-B1 | Process for preparing aromatic nitriles | ENICHEM SINTESI (IT) | 1995-09-06 | — | — | EP | claimed |
| EP-0441004-A1 | Process for preparing aromatic nitriles | ENICHEM SYNTHESIS S.p.A. (IT) | 1991-08-14 | — | — | EP | claimed |
| EP-0073372-B1 | PROCESS FOR PRODUCING 2,6-DIFLUOROBENZONITRILE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1984-08-01 | — | — | EP | claimed |
| US-4406841-A | HYDROGENATION OF 3-CHLORO- (OR 3,5-DICHLORO-2,6-DIFLUOROBENZONITRILE, PALLADIUM OR PLATINUM CATALYST | ISHIHARA SANGYO KAISHA LTD. (JP) | 1983-09-27 | — | — | US | claimed |
| EP-0073372-A1 | Process for producing 2,6-difluorobenzonitrile | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1983-03-09 | — | — | EP | claimed |
| JP-58189152-A | — | — | None | — | — | JP | disclosed |
| JP-58189151-A | — | — | None | — | — | JP | disclosed |
| US-20250242338-A1 | IRON PHOSPHIDE NANOPARTICLES, AND COMPOSITE BODY AND REDUCTION CATALYST EACH CONTAINING SAME | OSAKA UNIVERSITY (JP) | 2025-07-31 | — | — | US | disclosed |
| EP-4509462-A1 | IRON PHOSPHIDE NANOPARTICLES, AND COMPOSITE BODY AND REDUCTION CATALYST EACH CONTAINING SAME | OSAKA UNIVERSITY (JP) | 2025-02-19 | — | — | EP | disclosed |
| WO-2023200015-A1 | IRON PHOSPHIDE NANOPARTICLES, AND COMPOSITE BODY AND REDUCTION CATALYST EACH CONTAINING SAME | 国立大学法人大阪大学 | 2023-10-19 | — | — | WO | disclosed |
| CN-112851539-B | Preparation method of 2, 6-difluorobenzamide | 江苏扬农化工集团有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-112851539-A | Preparation method of 2, 6-difluorobenzamide | 江苏扬农化工集团有限公司 | 2021-05-28 | — | — | CN | disclosed |
| EP-0073372-B1 | PROCESS FOR PRODUCING 2,6-DIFLUOROBENZONITRILE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1984-08-01 | — | — | EP | disclosed |
| JP-S58189151-A | PREPARATION OF 3-CHLORO-2,6-DIFLUOROBENZONITRILE | ISHIHARA SANGYO KAISHA LTD | 1983-11-04 | — | — | JP | disclosed |
| JP-S58189152-A | PREPARATION OF 2,6-DIFLUOROBENZONITRILE | ISHIHARA SANGYO KAISHA LTD | 1983-11-04 | — | — | JP | disclosed |
| US-4406841-A | HYDROGENATION OF 3-CHLORO- (OR 3,5-DICHLORO-2,6-DIFLUOROBENZONITRILE, PALLADIUM OR PLATINUM CATALYST | ISHIHARA SANGYO KAISHA LTD. (JP) | 1983-09-27 | — | — | US | disclosed |
| EP-0073372-A1 | Process for producing 2,6-difluorobenzonitrile | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1983-03-09 | — | — | EP | disclosed |
| EP-0006999-B1 | A PROCESS FOR THE PRODUCTION OF 2-CHLOROBENZONITRILE DERIVATIVES | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-04-01 | — | — | EP | disclosed |
| US-4225534-A | FROM CHLORINATED 2-NITROBENZONITRILES | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-09-30 | — | — | US | disclosed |
| EP-0006999-A1 | A process for the production of 2-chlorobenzonitrile derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250242338-A1 | IRON PHOSPHIDE NANOPARTICLES, AND COMPOSITE BODY AND REDUCTION CATALYST EACH CONTAINING SAME | FECH, PI4K2A, PHOSPHO1 | ALDH1A1 4269/4885CYP3A4 3109/4885MAPK1 2739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.