Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL402993 | 0.95 | TBXAS1 (0.34) | TBXAS1 | |
| SCHEMBL8465355 | 0.87 | TET2 (0.31) | — | |
| SCHEMBL400291 | 0.86 | TBXAS1 (0.36) | TBXAS1 | |
| SCHEMBL442700 | 0.86 | TBXAS1 (0.36) | TBXAS1 | |
| SCHEMBL9743626 | 0.84 | TBXAS1 (0.36) | TBXAS1 | |
| SCHEMBL675562 | 0.84 | TBXAS1 (0.37) | TBXAS1 | |
| SCHEMBL1803453 | 0.83 | TBXAS1 (0.35) | TBXAS1 | |
| SCHEMBL399741 | 0.81 | TBXAS1 (0.34) | TBXAS1 | |
| SCHEMBL1802295 | 0.81 | TBXAS1 (0.34) | TBXAS1 | |
| SCHEMBL8466016 | 0.81 | TBXAS1 (0.34) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3861039-B1 | HYDROGEL COMPOSITIONS | OPHTALMIC CIE (FR) | 2023-11-01 | — | — | EP | claimed |
| EP-2077292-B1 | Polysiloxane-based prepolymer and hydrogel | FAR EASTERN NEW CENTURY CORP (TW) | 2013-08-14 | — | — | EP | claimed |
| EP-0657751-B1 | Soft ocular lens material | MENICON CO LTD (JP) | 2003-04-23 | — | — | EP | claimed |
| US-5883152-A | HARD CONTACT LENS CONSISTING OF A COPOLYMER OF CARBOXYLIC ACID ESTER MONOMER, TRIS(TRIMETHYLSILOXY)SILYLPROPYL(METH)ACRYLATE, AND COPOLYMERIZABLE MONOMER | NIPPON OIL AND FATS CO., LTD. (JP) | 1999-03-16 | — | — | US | claimed |
| EP-0446372-B1 | CONTACT LENS | HOYA CORP (JP) | 1995-09-13 | — | — | EP | claimed |
| WO-2023209855-A1 | ADDITION TYPE POLYMER AND SILICONE HYDROGEL LENS MATERIAL | 株式会社メニコン | 2023-11-02 | — | — | WO | disclosed |
| EP-3756874-A2 | PINHOLE CONTACT LENS FORMING JIG | Seed Co., Ltd. (JP) | 2020-12-30 | — | — | EP | disclosed |
| US-10125209-B2 | Macromonomer mixture, terminal-reactive polymer mixture, intermediate for macromonomer and silicone hydrogel | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2018-11-13 | — | — | US | disclosed |
| US-20160272766-A1 | POLYSILOXANE-BASED MACROMONOMER FOR OPHTHALMIC LENS AND OPHTHALMIC LENS USING THE SAME | MENICON CO., LTD. (JP) | 2016-09-22 | — | — | US | disclosed |
| US-9238715-B2 | Polymerizable composition for ophthalmic and medical use and antimicrobial composition obtained by polymerizing the polymerizable composition | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-01-19 | — | — | US | disclosed |
| EP-2650021-B1 | MEDICAL DEVICE FOR CONTROLLED RELEASE OF DRUG | SEED CO LTD (JP) | 2015-12-09 | — | — | EP | disclosed |
| US-9056880-B2 | Process for producing hydrolysis-resistant silicone compounds | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2015-06-16 | — | — | US | disclosed |
| US-20080004401-A1 | SILOXANYL MATERIALS FOR MOLDED PLASTICS | JOHNSON & JOHNSON VISION CARE, INC. | 2008-01-03 | — | — | US | disclosed |
| US-20080004383-A1 | ACRYLOYL MATERIALS FOR MOLDED PLASTICS | TORAY INDUSTRIES, INC. (JP) | 2008-01-03 | — | — | US | disclosed |
| US-7261844-B2 | For effectively reducing a period of time for discoloring a contact lens from a colored state to an uncolored state | MENICON CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| EP-1806614-A1 | HIGHLY OXYGEN-PERMEABLE HYDRATED OCULAR LENS | Seed Co., Ltd. (JP) | 2007-07-11 | — | — | EP | disclosed |
| US-20070100018-A1 | Functionalized dyes and use thereof in ophthalmic lens material | OPHTEC B.V. (NL) | 2007-05-03 | — | — | US | disclosed |
| US-20050243273-A1 | Photochromic contact lens having excellent discoloring characteristic | MENICON CO., LTD. (JP) | 2005-11-03 | — | — | US | disclosed |
| EP-1176454-B1 | OCULAR LENS MATERIALS AND PROCESS FOR PRODUCING THE SAME | MENICON CO LTD (JP) | 2003-07-30 | — | — | EP | disclosed |
| US-5519070-A | FLUORINE, ALKOXY POLYSILOXANE COPOLYMERS FOR INTRAOCULAR LENSES | MENICON CO., LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004383-A1 | ACRYLOYL MATERIALS FOR MOLDED PLASTICS | ACR, HAAO, PORCN | TBXAS1 1033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.