Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | FPR1 | P21462 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4563526 | 0.99 | MAPT (0.42) | MAPTMAOAFPR1ABCB1LTB4R | |
| SCHEMBL27799994 | 0.79 | GLA (0.56) | MAPTMAOAADORA2AADORA3ADORA1 | |
| SCHEMBL4422470 | 0.78 | STING1 (0.65) | ABCB1LTB4RGLASTING1KDM4E | |
| SCHEMBL3649676 | 0.77 | GLA (0.57) | MAPTMAOAADORA2AADORA3ADORA1 | |
| SCHEMBL4563524 | 0.76 | STING1 (0.67) | ABCB1LTB4RGLASTING1KDM4E | |
| SCHEMBL4422473 | 0.75 | STING1 (0.65) | ABCB1LTB4RGLASTING1KDM4E | |
| SCHEMBL4849595 | 0.75 | MAOA (0.68) | MAPTMAOAADORA2AADORA3ADORA1 | |
| SCHEMBL4422465 | 0.74 | GLA (0.51) | LTB4RGLASTING1KDM4EGAA | |
| SCHEMBL7235919 | 0.72 | KDM4E (0.49) | MAPTMAOAADORA2AADORA3ADORA1 | |
| SCHEMBL11747126 | 0.70 | ADORA2A (0.40) | FPR1ADORA2AADORA3ADORA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009156459-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-12-30 | — | — | WO | claimed |
| WO-2009156459-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-12-30 | — | — | WO | disclosed |