Propionamide

Propionamide

SCHEMBL28035985

CCC(N)=O.CCOCC

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.48
SOAT1 P35610 1/20 0.41
ALDH1A1 P00352 8/20 0.40
TSHR P16473 2/20 0.40
TDP1 Q9NUW8 3/20 0.37
FFAR3 O14843 1/20 0.37
LMNA P02545 2/20 0.36
HSD17B10 Q99714 2/20 0.36
KDM4E B2RXH2 1/20 0.35
GMNN O75496 1/20 0.35
USP2 O75604 1/20 0.35
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.35
GLA P06280 1/20 0.35
POLB P06746 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35
THPO P40225 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL1011439 0.87
Ether SCHEMBL28156440 0.85 ALOX15 (0.46) ALOX15SOAT1ALDH1A1TSHRTDP1
Ether SCHEMBL4328551 0.85 ALOX15 (0.46) ALOX15SOAT1ALDH1A1TSHRTDP1
Ether SCHEMBL15110284 0.85 ALOX15 (0.46) ALOX15SOAT1ALDH1A1TSHRTDP1
Ether SCHEMBL9560131 0.85 ALOX15 (0.46) ALOX15SOAT1ALDH1A1TSHRTDP1
Ether SCHEMBL173703 0.84
Ether SCHEMBL442290 0.84
Propionamide SCHEMBL6361 0.83
Propionamide SCHEMBL27662186 0.83 TDP1 (0.50) ALOX15SOAT1ALDH1A1TSHRTDP1
Ether SCHEMBL2549388 0.82 ALDH1A1 (0.46) ALOX15SOAT1ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104953176-A Processing method of low-color-number glycol bis(cyanoproprl) ether FUJIAN MATTER STRUCTURE 2015-09-30 CN disclosed