Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 5/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | UNG | P13051 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Formylbenzoic Acid SCHEMBL4423592 | 0.87 | UNG (0.66) | P4HBTTRAPPUNGPTPN1 | |
| 3-Formylbenzoic Acid SCHEMBL4423601 | 0.87 | UNG (0.66) | P4HBTTRAPPUNGPTPN1 | |
| SCHEMBL18098004 | 0.87 | P4HB (0.68) | P4HBTTRAPPPTPN1EPHX2 | |
| SCHEMBL2280674 | 0.87 | TTR (0.58) | TTRAPPUNGPTPN1EPHX2 | |
| SCHEMBL2280675 | 0.87 | TTR (0.58) | TTRAPPUNGPTPN1EPHX2 | |
| SCHEMBL19217013 | 0.83 | P4HB (0.56) | P4HBTTRAPPPTPN1EPHX2 | |
| SCHEMBL1410893 | 0.81 | P4HB (0.57) | P4HBTTRAPPUNGPTPN1 | |
| SCHEMBL31021318 | 0.81 | P4HB (0.57) | P4HBTTRAPPUNGPTPN1 | |
| SCHEMBL1410896 | 0.81 | P4HB (0.57) | P4HBTTRAPPUNGPTPN1 | |
| SCHEMBL47068 | 0.80 | ALDH1A1 (0.61) | P4HBUNGALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069291-A1 | HDAC INHIBITORS | Chroma Therapeutics Limited (GB) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008040934-A1 | HDAC INHIBITORS | CHROMA THERAPEUTICS LTD. (GB) | 2008-04-10 | — | — | WO | disclosed |