⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442366 | 0.83 | — | — | |
| SCHEMBL2952874 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL13493927 | 0.72 | TSHR (0.33) | — | |
| SCHEMBL7081474 | 0.72 | TSHR (0.30) | — | |
| SCHEMBL9549066 | 0.72 | TSHR (0.30) | — | |
| SCHEMBL2522703 | 0.72 | TSHR (0.30) | — | |
| SCHEMBL1096715 | 0.72 | TSHR (0.30) | — | |
| SCHEMBL701682 | 0.70 | — | — | |
| SCHEMBL7153188 | 0.69 | — | — | |
| SCHEMBL3503381 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124745-B2 | Polycyclic sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation | ISIS PHARMACEUTICALS, INC (US) | 2012-02-28 | — | — | US | claimed |
| US-20100216982-A1 | POLYCYCLIC SUGAR SURROGATE-CONTAINING OLIGOMERIC COMPOUNDS AND COMPOSITIONS FOR USE IN GENE MODULATION | Isis Pharmaceutiacls, Inc. (US) | 2010-08-26 | — | — | US | claimed |
| US-5969128-A | NUCLEIC ACID PROBES WITH TERMINAL PRIMARY AMINE GROUPS IN A CONFIGURATION FOR ATTACHMENT OF MARKER WHICH IS DETECTABLE BY PRODUCTION OF COLOR OR LIGHT; DIAGNOSIS OF GENETIC DISORDERS, ONCOGENES, VIRAL/BACTERIA/PARASITIC DISEASES | LA REGION WALLONE (BE) | 1999-10-19 | — | — | US | disclosed |
| EP-0684954-B1 | NUCLEIC ACID PROBES CHEMICALLY 5'(OH)- AND/OR 3'(OH)-MODIFIED FOR INSERTING ONE OR MORE NON-RADIOACTIVE LABELING ELEMENTS THEREAT, AND METHOD FOR PREPARING SAME | WALLONE REGION (BE) | 1998-07-22 | — | — | EP | disclosed |
| EP-0684954-A1 | NUCLEIC ACID PROBES CHEMICALLY 5'(OH)- AND/OR 3'(OH)-MODIFIED FOR INSERTING ONE OR MORE NON-RADIOACTIVE LABELING ELEMENTS THEREAT, AND METHOD FOR PREPARING SAME | LA REGION WALLONNE (BE) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994019364-A2 | NUCLEIC ACID PROBES CHEMICALLY 5'(OH)- AND/OR 3'(OH)-MODIFIED FOR INSERTING ONE OR MORE NON-RADIOACTIVE LABELING ELEMENTS THEREAT, AND METHOD FOR PREPARING SAME | LA REGION WALLONNE (BE) | 1994-09-01 | — | — | WO | disclosed |