⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3638619 | 0.82 | TSHR (0.32) | — | |
| SCHEMBL442364 | 0.81 | — | — | |
| SCHEMBL701684 | 0.70 | — | — | |
| SCHEMBL23783512 | 0.68 | — | — | |
| SCHEMBL6014342 | 0.68 | — | — | |
| SCHEMBL9549154 | 0.65 | — | — | |
| SCHEMBL78637 | 0.64 | TSHR (0.35) | — | |
| SCHEMBL9436377 | 0.64 | TSHR (0.35) | — | |
| SCHEMBL30898370 | 0.64 | TSHR (0.35) | — | |
| SCHEMBL7873521 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124745-B2 | Polycyclic sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation | ISIS PHARMACEUTICALS, INC (US) | 2012-02-28 | — | — | US | claimed |
| US-20100216982-A1 | POLYCYCLIC SUGAR SURROGATE-CONTAINING OLIGOMERIC COMPOUNDS AND COMPOSITIONS FOR USE IN GENE MODULATION | Isis Pharmaceutiacls, Inc. (US) | 2010-08-26 | — | — | US | claimed |