⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701684 | 0.83 | — | — | |
| SCHEMBL1096715 | 0.81 | TSHR (0.30) | — | |
| SCHEMBL9549066 | 0.81 | TSHR (0.30) | — | |
| SCHEMBL1589779 | 0.79 | — | — | |
| SCHEMBL3503381 | 0.79 | — | — | |
| SCHEMBL1856538 | 0.78 | — | — | |
| SCHEMBL28180136 | 0.77 | — | — | |
| SCHEMBL12179917 | 0.77 | — | — | |
| SCHEMBL1500489 | 0.76 | — | — | |
| SCHEMBL55353 | 0.76 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9540515-B2 | Fluorescence quenching azo dyes, their methods of preparation and use | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2017-01-10 | — | — | US | disclosed |
| US-20130116415-A1 | FLUORESCENCE QUENCHING AZO DYES, THEIR METHODS OF PREPARATION AND USE | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2013-05-09 | — | — | US | disclosed |
| US-8377641-B2 | Fluorescence quenching azo dyes, their methods of preparation and use | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2013-02-19 | — | — | US | disclosed |
| US-20120064633-A1 | FLUORESCENCE QUENCHING AZO DYES, THEIR METHODS OF PREPARATION AND USE | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2012-03-15 | — | — | US | disclosed |
| US-8084588-B2 | Fluorescence quenching azo dyes, their methods of preparation and use | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-7687618-B2 | reaction of an oligonucleotide having a labile protecting group bound to a terminal hydroxy group, and a labeling compound; nucleophilic substitution reaction; lower reaction times and yields are advantageous for the user because they permit a high throughput with low technical requirements | NIMBLEGEN SYSTEMS GMBH (DE) | 2010-03-30 | — | — | US | disclosed |
| WO-2009143369-A2 | METHOD OF PREPARING NUCLEOSIDES AND ANALOGS THEREOF WITHOUT USING CHROMATOGRAPHY | ISIS PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | WO | disclosed |
| US-20090053821-A1 | FLUORESCENCE QUENCHING AZO DYES, THEIR METHODS OF PREPARATION AND USE | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2009-02-26 | — | — | US | disclosed |
| US-7439341-B2 | Fluorescence quenching azo dyes, their methods of preparation and use | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2008-10-21 | — | — | US | disclosed |
| US-20060122382-A1 | Method of manufacturing labelled oligonucleotide conjugates | NIMBLEGENSYSTEMS GMBH (DE) | 2006-06-08 | — | — | US | disclosed |
| EP-1476407-A2 | METHODS OF PRODUCING PHOSPHITYLATED COMPOUNDS | Honeywell International Inc. (US) | 2004-11-17 | — | — | EP | disclosed |
| WO-2004035600-A1 | METHOD OF MANUFACTURING LABELLED OLIGONUCLEOTIDE CONJUGATES | CHEMOGENIX GMBH (DE) | 2004-04-29 | — | — | WO | disclosed |
| WO-2003072586-A2 | METHODS OF PRODUCING PHOSPHITYLATED COMPOUNDS | HONEYWELL INTERNATIONAL INC. (US) | 2003-09-04 | — | — | WO | disclosed |
| EP-1001996-A1 | COMPLEX CHEMICAL COMPOUND, SYNTHESIS AND VARIOUS APPLICATIONS OF SAID COMPOUND | BIO MERIEUX (FR) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999007749-A1 | COMPLEX CHEMICAL COMPOUND, SYNTHESIS AND VARIOUS APPLICATIONS OF SAID COMPOUND | BIO MERIEUX (FR) | 1999-02-18 | — | — | WO | disclosed |
| EP-0451141-B1 | IMMOBILIZED SEQUENCE-SPECIFIC PROBES | HOFFMANN LA ROCHE (CH) | 1998-11-18 | — | — | EP | disclosed |
| US-5766550-A | NON-SWELLABLE, INSOLUBLE, STABLE MATRIX ONTO WHICH IS ADSORBED A REAGENT TO BE COUPLED TO AN IMMOBILIZED OLIGONUCLEOTIDE PRECURSOR | CITY OF HOPE (US) | 1998-06-16 | — | — | US | disclosed |
| WO-1996028248-A1 | DISPOSABLE REAGENT STORAGE AND DELIVERY CARTRIDGE | CITY OF HOPE (US) | 1996-09-19 | — | — | WO | disclosed |
| EP-0451141-A1 | IMMOBILIZED SEQUENCE-SPECIFIC PROBES | F. HOFFMANN-LA ROCHE AG (CH) | 1991-10-16 | — | — | EP | disclosed |
| WO-1989011548-A1 | IMMOBILIZED SEQUENCE-SPECIFIC PROBES | CETUS CORPORATION (US) | 1989-11-30 | — | — | WO | disclosed |