Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9549066 | 0.96 | TSHR (0.30) | TSHRNLRP3 | |
| SCHEMBL1500489 | 0.90 | — | — | |
| SCHEMBL1589779 | 0.81 | — | — | |
| SCHEMBL442366 | 0.81 | — | — | |
| SCHEMBL3503381 | 0.81 | — | — | |
| SCHEMBL6231122 | 0.78 | — | — | |
| SCHEMBL9792927 | 0.76 | — | — | |
| SCHEMBL17689313 | 0.74 | NLRP3 (0.37) | TSHRNLRP3 | |
| SCHEMBL6325642 | 0.74 | TSHR (0.33) | TSHR | |
| SCHEMBL1500279 | 0.73 | ALDH1A1 (0.41) | TSHRNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125413-A1 | UNIVERSAL SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE SYNTHESIS | AM CHEMICALS LLC (US) | 2026-05-07 | — | — | US | disclosed |
| US-12397013-B2 | Extrahepatic delivery | ALNYLAM PHARMACEUTICALS, INC. (US) | 2025-08-26 | — | — | US | disclosed |
| EP-4577539-A1 | UNIVERSAL SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE SYNTHESIS | AM Chemicals Llc (US) | 2025-07-02 | — | — | EP | disclosed |
| US-20240358738-A1 | EXTRAHEPATIC DELIVERY | BANK OF AMERICA, N.A. | 2024-10-31 | — | — | US | disclosed |
| US-12005074-B2 | Extrahepatic delivery | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-06-11 | — | — | US | disclosed |
| WO-2024044792-A1 | UNIVERSAL SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE SYNTHESIS | AM CHEMICALS LLC (US) | 2024-02-29 | — | — | WO | disclosed |
| US-20240009225-A1 | EXTRAHEPATIC DELIVERY | BANK OF AMERICA, N.A. | 2024-01-11 | — | — | US | disclosed |
| US-20230086177-A1 | PROCESS FOR PREPARING POLYETHER CARBONATE POLYOLS | COVESTRO DEUTSCHLAND AG (DE) | 2023-03-23 | — | — | US | disclosed |
| US-20230069332-A1 | PROCESS FOR PRODUCING POLYETHER CARBONATE POLYOLS | COVESTRO DEUTSCHLAND AG (DE) | 2023-03-02 | — | — | US | disclosed |
| US-20220411578-A1 | PROCESS FOR PRODUCING POLYETHER CARBONATE POLYOLS | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2022-12-29 | — | — | US | disclosed |
| US-5914396-A | 2'-O-modified nucleosides and phosphoramidites | ISIS PHARMACEUTICALS, INC. (US) | 1999-06-22 | — | — | US | disclosed |
| US-5856466-A | Process for the preparation of 2'-O-alkyl purine phosphoramidites | ISIS PHARMACEUTICALS, INC. (US) | 1999-01-05 | — | — | US | disclosed |
| US-5646265-A | Process for the preparation of 2'-O-alkyl purine phosphoramidites | ISIS PHARMCEUTICALS, INC. (US) | 1997-07-08 | — | — | US | disclosed |
| EP-0728139-A1 | AMINE-DERIVATIZED NUCLEOSIDES AND OLIGONUCLEOSIDES | ISIS PHARMACEUTICALS, INC. (US) | 1996-08-28 | — | — | EP | disclosed |
| US-5506351-A | Process for the preparation of 2'-O-alkyl guanosine and related compounds | ISIS PHARMACEUTICALS (US) | 1996-04-09 | — | — | US | disclosed |
| EP-0651759-A4 | NOVEL 2'-O-ALKYL NUCLEOSIDES AND PHOSPHORAMIDITES PROCESSES FOR THE PREPARATION AND USES THEREOF. | ISIS PHARMACEUTICALS INC (US) | 1995-10-25 | — | — | EP | disclosed |
| EP-0651759-A1 | NOVEL 2'-O-ALKYL NUCLEOSIDES AND PHOSPHORAMIDITES PROCESSES FOR THE PREPARATION AND USES THEREOF | ISIS PHARMACEUTICALS, INC. (US) | 1995-05-10 | — | — | EP | disclosed |
| WO-1995006659-A1 | AMINE-DERIVATIZED NUCLEOSIDES AND OLIGONUCLEOSIDES | ISIS PHARMACEUTICALS, INC. (US) | 1995-03-09 | — | — | WO | disclosed |
| WO-1994002501-A1 | NOVEL 2'-O-ALKYL NUCLEOSIDES AND PHOSPHORAMIDITES PROCESSES FOR THE PREPARATION AND USES THEREOF | ISIS PHARMACEUTICALS, INC. (US) | 1994-02-03 | — | — | WO | disclosed |
| US-5179200-A | N4-(3-PHENYLPROPRIONYL)-2'-DEOXYCYTIDINE | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1993-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240358738-A1 | EXTRAHEPATIC DELIVERY | RNASE1, SLC10A1, FABP1 | TSHR 662/4885NLRP3 4082/4885 |
| US-12005074-B2 | Extrahepatic delivery | RNASE1, SLC10A1, FABP1 | TSHR 662/4885NLRP3 4082/4885 |
| US-20240009225-A1 | EXTRAHEPATIC DELIVERY | RNASE1, SLC10A1, FABP1 | TSHR 662/4885NLRP3 4082/4885 |
| US-20260125413-A1 | UNIVERSAL SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE SYNTHESIS | SSU72, NSUN2, POLR2H | TSHR 2360/4885NLRP3 4734/4885 |
| US-12397013-B2 | Extrahepatic delivery | RNASE1, LDLR, HAVCR2 | TSHR 885/4885NLRP3 4022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.