SCHEMBL6572582

SCHEMBL6572582

CC(C)(c1ccc(O)c(Br)c1)c1cc(Br)c(O)c(Br)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 1.00
ALOX12 P18054 2/20 1.00
HSD17B10 Q99714 4/20 0.73
TSHR P16473 4/20 0.73
CYP3A4 P08684 4/20 0.73
ALDH1A1 P00352 4/20 0.73
HPGD P15428 3/20 0.73
HIF1A Q16665 3/20 0.73
TDP1 Q9NUW8 3/20 0.73
RECQL P46063 2/20 0.73
CASP1 P29466 1/20 0.73
CHEK1 O14757 1/20 0.56
DAPK3 O43293 1/20 0.56
RET P07949 1/20 0.56
PDGFRB P09619 1/20 0.56
PIM1 P11309 1/20 0.56
PDGFRA P16234 1/20 0.56
KDR P35968 1/20 0.56
MAPK8 P45983 1/20 0.56
RPS6KA3 P51812 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29466259 1.00 ALOX15 (1.00) ALOX15ALOX12HSD17B10TSHRCYP3A4
SCHEMBL29378598 0.92 ALOX15 (0.85) ALOX15ALOX12HSD17B10TSHRCYP3A4
SCHEMBL29361821 0.92 ALOX15 (0.85) ALOX15ALOX12HSD17B10TSHRCYP3A4
SCHEMBL121262 0.92 ALOX15 (0.85) ALOX15ALOX12HSD17B10TSHRCYP3A4
SCHEMBL7004372 0.89 ALOX15 (0.80) ALOX15ALOX12HSD17B10TSHRCYP3A4
SCHEMBL14760246 0.89 ALOX15 (0.80) ALOX15ALOX12HSD17B10TSHRCYP3A4
SCHEMBL11567514 0.88 ALOX15 (0.86) ALOX15ALOX12HSD17B10TSHRCYP3A4
Propane SCHEMBL4424428 0.86 ALOX15 (0.76) ALOX15ALOX12HSD17B10TSHRCYP3A4
SCHEMBL671781 0.86 ALOX15 (0.75) ALOX15ALOX12HSD17B10TSHRCYP3A4
SCHEMBL18647 0.85 TSHR (1.00) ALOX15ALOX12HSD17B10TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114835998-B Dielectric elastomer film capable of overcoming force-electricity instability and self-repairing, preparation method and dielectric driver 浙江大学 2023-05-12 CN claimed
CN-114835998-A Self-repairable dielectric elastomer film capable of overcoming power and electricity instability, preparation method and dielectric driver 浙江大学 2022-08-02 CN claimed
US-20040266885-A1 Wood preservative compositions BROMINE COMPOUNDS LTD. (IL) 2004-12-30 US claimed
EP-1409212-A1 WOOD PRESERVATIVE COMPOSITIONS Bromine Compounds Ltd. (IL) 2004-04-21 EP claimed
WO-2003009981-A1 WOOD PRESERVATIVE COMPOSITIONS BROMINE COMPOUNDS LTD. (IL) 2003-02-06 WO claimed
CN-114835998-B Dielectric elastomer film capable of overcoming force-electricity instability and self-repairing, preparation method and dielectric driver 浙江大学 2023-05-12 CN disclosed
CN-114835998-A Self-repairable dielectric elastomer film capable of overcoming power and electricity instability, preparation method and dielectric driver 浙江大学 2022-08-02 CN disclosed
US-20040266885-A1 Wood preservative compositions BROMINE COMPOUNDS LTD. (IL) 2004-12-30 US disclosed
EP-1409212-A1 WOOD PRESERVATIVE COMPOSITIONS Bromine Compounds Ltd. (IL) 2004-04-21 EP disclosed
WO-2003009981-A1 WOOD PRESERVATIVE COMPOSITIONS BROMINE COMPOUNDS LTD. (IL) 2003-02-06 WO disclosed
US-6313355-B1 Process for the preparation of tetrabromobisphenol-A ALBEMARLE CORPORATION 2001-11-06 US disclosed
US-6300527-B1 BROMINATING BISPHENOL A IN PRESENCE OF EXCESS UNREACTED BROMINE IN REACTION MASS HAVING LIQUID PHASE INTO WHICH REACTANTS ARE FED AND FROM WHICH PRODUCT IS PRECIPITATED AND WHICH CONTAINS HYDROGEN BROMIDE TO PREVENT DISCOLORATION ALBEMARLE CORPORATION 2001-10-09 US disclosed
US-6235946-B1 CONCURRENT FEEDING OF BISPHENOL A AND SOLVENT WITH HYDROBROMIC ACID AND HYDROGEN PEROXIDE ALBEMARLE CORPORATION 2001-05-22 US disclosed
US-6218584-B1 BROMINATING BISPHENOL A; DISCOLORATION INHIBITION WITH HYDROGEN BROMIDE; PRECIPITATION; HIGH YIELD ALBEMARLE CORPORATION 2001-04-17 US disclosed
US-6147264-A BROMINATING BISPHENOL A IN LIQUID PHASE MEDIUM IN WHICH TETRABROMOBISPHENOL A IS RELATIVELY INSOLUBLE, USING STOICHIOMETRIC DEFICIENCY OF BROMINE TO FORM PRECIPITATE IN REACTION MASS, RECOVERING PRECIPITATE, RECOVERING PRODUCT ALBEMARLE CORPORATION (US) 2000-11-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040266885-A1 Wood preservative compositions CYP4X1, CYP1A1, MANBA ALOX15 404/4885ALOX12 459/4885HSD17B10 1523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.