SCHEMBL4424433

SCHEMBL4424433

CCCCC(C)(c1ccc(O)c(Br)c1)c1ccc(O)c(Br)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 12/20 0.51
ESR2 Q92731 6/20 0.51
ALOX15 P16050 2/20 0.51
ALOX12 P18054 1/20 0.51
AR P10275 2/20 0.42
CHEK1 O14757 1/20 0.41
FYN P06241 1/20 0.41
PDGFRB P09619 1/20 0.41
PIM1 P11309 1/20 0.41
FGFR1 P11362 1/20 0.41
FLT1 P17948 1/20 0.41
GRK5 P34947 1/20 0.41
MAP2K2 P36507 1/20 0.41
MAPK8 P45983 1/20 0.41
CDK8 P49336 1/20 0.41
RPS6KA3 P51812 1/20 0.41
PRKX P51817 1/20 0.41
JAK3 P52333 1/20 0.41
LIMK1 P53667 1/20 0.41
BTK Q06187 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2028816 0.83 ESR1 (0.74) ESR1ESR2AR
SCHEMBL7943487 0.82 ALOX15 (0.58) ESR1ESR2ALOX15ALOX12AR
SCHEMBL10551142 0.81 TSHR (0.60) ESR1ESR2ALOX15ALOX12CHEK1
SCHEMBL7943504 0.79 ALOX15 (0.58) ESR1ESR2ALOX15ALOX12AR
SCHEMBL14760247 0.79 ALOX15 (0.54) ESR1ESR2ALOX15ALOX12AR
SCHEMBL6056720 0.78 ESR1 (0.67) ESR1ESR2ARCNR1CNR2
SCHEMBL31738904 0.78 ESR1 (0.67) ESR1ESR2ARCNR1CNR2
Propane SCHEMBL4424428 0.77 ALOX15 (0.76) ESR1ESR2ALOX15ALOX12AR
SCHEMBL10748415 0.77 ESR1 (0.65) ESR1ESR2ARCNR1CNR2
SCHEMBL2860135 0.77 ESR1 (0.65) ESR1ESR2ARCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021126796-A1 MOLDED ARTICLES COMPRISING A POST-CONSUMER RECYCLE POLYCARBONATE AND METHOD FOR THE MANUFACTURE THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2021-06-24 WO disclosed
EP-3713765-A2 PANEL, INTEGRATED STRUCTURE, AND METHOD SABIC Global Technologies B.V. (NL) 2020-09-30 EP disclosed
WO-2019102349-A2 PANEL, INTEGRATED STRUCTURE, AND METHOD SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-05-31 WO disclosed
EP-2066727-A1 POLYCARBONATE-POLYSILOXANE COPOLYMERS, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM Sabic Innovative Plastics IP B.V. (NL) 2009-06-10 EP disclosed
WO-2008042500-A1 POLYCARBONATE-POLYSILOXANE COPOLYMERS, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-04-10 WO disclosed