Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 12/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.41 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | GRK5 | P34947 | 1/20 | 0.40 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5873699 | 0.86 | ESR1 (0.57) | ESR1ESR2ARCHEK1FYN | |
| SCHEMBL5953180 | 0.84 | CYP2C9 (0.62) | ALOX15ALOX12HSD17B10TSHRHIF1A | |
| SCHEMBL671782 | 0.84 | ALOX15 (0.51) | ALOX15ALOX12HSD17B10TSHRHIF1A | |
| SCHEMBL674211 | 0.83 | ALOX15 (0.46) | ALOX15ALOX12HSD17B10TSHRHIF1A | |
| SCHEMBL7969192 | 0.83 | TSHR (0.59) | ALOX15ALOX12HSD17B10TSHRHIF1A | |
| SCHEMBL14760246 | 0.81 | ALOX15 (0.80) | ALOX15ALOX12HSD17B10TSHRHIF1A | |
| SCHEMBL10935943 | 0.81 | ESR1 (0.54) | ESR1ESR2ARCHEK1FYN | |
| SCHEMBL7972245 | 0.80 | ESR1 (0.54) | ALOX15ALOX12HSD17B10TSHRHIF1A | |
| SCHEMBL4424433 | 0.79 | ESR1 (0.51) | ALOX15ALOX12HSD17B10TSHRHIF1A | |
| SCHEMBL11362209 | 0.79 | ALOX15 (0.65) | ALOX15ALOX12HSD17B10TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2277936-B1 | Method of preparing polycarbonate resin | LG CHEMICAL LTD (KR) | 2013-03-13 | — | — | EP | disclosed |