Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8671097 | 0.76 | HRH3 (0.39) | HRH3DRD2DRD4OPRM1DRD3 | |
| SCHEMBL8669673 | 0.74 | DRD2 (0.37) | MEN1KMT2ADRD2DRD4SMN1; SMN2 | |
| SCHEMBL7428125 | 0.69 | DRD4 (0.47) | MEN1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL5752231 | 0.66 | KCNA3 (0.36) | MEN1KMT2ADRD2DRD4SMN1; SMN2 | |
| SCHEMBL4424640 | 0.66 | MEN1 (0.36) | MEN1KMT2ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11587635 | 0.66 | MEN1 (0.81) | MEN1KMT2ADRD4TAAR1 | |
| SCHEMBL8935841 | 0.66 | TSHR (0.48) | MEN1KMT2ASMN1; SMN2KDM4ETSHR | |
| SCHEMBL198134 | 0.65 | TSHR (0.52) | MEN1KMT2AHRH3SMN1; SMN2ALDH1A1 | |
| SCHEMBL26604377 | 0.64 | MEN1 (0.51) | MEN1KMT2AHRH3TSHRACACB | |
| SCHEMBL7357672 | 0.64 | CCR1 (0.40) | MEN1KMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973404-B1 | MALONONITRILE COMPOUNDS | MERIAL INC (US) | 2015-10-28 | — | — | EP | claimed |
| US-20090326012-A1 | Malononitrile Compounds | MERIAL, INC. | 2009-12-31 | — | — | US | claimed |
| EP-1973404-B1 | MALONONITRILE COMPOUNDS | MERIAL INC (US) | 2015-10-28 | — | — | EP | disclosed |
| US-5648370-A | 7-(2-aminoethyl) benzothiazolones | ASTRA PHARMACEUTICALS LIMITED (GB) | 1997-07-15 | — | — | US | disclosed |
| WO-1993023385-A1 | BIOLOGICALLY ACTIVE AMINES | FISONS PLC (GB) | 1993-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326012-A1 | Malononitrile Compounds | NR0B2, NR2C2, NR0B1 | MEN1 3641/4885KMT2A 3154/4885HRH3 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.