Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LHCGR | P22888 | 7/20 | 0.45 |
| ▸ | FSHR | P23945 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 3/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034074 | 0.92 | LHCGR (0.51) | LHCGRFSHRTSHRMAP4K4 | |
| SCHEMBL4422529 | 0.89 | JAK3 (0.42) | LHCGRFSHRTSHRBRAFMAP4K4 | |
| SCHEMBL6218317 | 0.83 | LHCGR (0.60) | LHCGRFSHRTSHRBRAF | |
| SCHEMBL4425812 | 0.83 | LHCGR (0.49) | LHCGRFSHRTSHRMAP4K4 | |
| SCHEMBL4423532 | 0.82 | MAP4K4 (0.51) | MAP4K4 | |
| SCHEMBL4432379 | 0.81 | LHCGR (0.43) | LHCGRFSHRTSHRBRAFMAP4K4 | |
| SCHEMBL4423903 | 0.80 | LHCGR (0.54) | LHCGRFSHRTSHRBRAFKMT2A | |
| SCHEMBL4418728 | 0.77 | LHCGR (0.57) | LHCGRTSHRBRAF | |
| SCHEMBL4425814 | 0.77 | LHCGR (0.40) | LHCGRFSHRTSHRBRAFMAP4K4 | |
| SCHEMBL5026955 | 0.76 | BRAF (0.57) | LHCGRFSHRTSHRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618963-B2 | Bicyclic heteroaromatic compounds | N.V. ORGANON (NL) | 2009-11-17 | — | — | US | disclosed |
| US-20070197527-A1 | Bicyclic heteroaromatic compounds | N.V. ORGANON (NL) | 2007-08-23 | — | — | US | disclosed |
| EP-1322651-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS | Akzo Nobel N.V. (NL) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002024703-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS | AKZO NOBEL N.V. (NL) | 2002-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197527-A1 | Bicyclic heteroaromatic compounds | NR5A1, CYP19A1, FSHR | LHCGR 10/4885FSHR 3/4885TSHR 517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.