Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LHCGR | P22888 | 10/20 | 0.51 |
| ▸ | FSHR | P23945 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4425074 | 0.92 | LHCGR (0.45) | LHCGRFSHRTSHRMAP4K4 | |
| SCHEMBL4425812 | 0.92 | LHCGR (0.49) | LHCGRFSHRTSHRMAP4K4GAA | |
| SCHEMBL4422167 | 0.85 | LHCGR (0.55) | LHCGRFSHRTSHRLMNA | |
| SCHEMBL4430421 | 0.84 | LHCGR (0.66) | LHCGRFSHRTSHRLMNA | |
| SCHEMBL4423875 | 0.81 | LHCGR (0.69) | LHCGRFSHRTSHR | |
| SCHEMBL4422529 | 0.81 | JAK3 (0.42) | LHCGRFSHRTSHRMAP4K4LMNA | |
| SCHEMBL6218317 | 0.78 | LHCGR (0.60) | LHCGRFSHRTSHR | |
| SCHEMBL6222004 | 0.78 | LHCGR (0.68) | LHCGRFSHRTSHR | |
| SCHEMBL4423532 | 0.76 | MAP4K4 (0.51) | MAP4K4LMNAHTT | |
| SCHEMBL27502615 | 0.75 | LHCGR (0.50) | LHCGRFSHRTSHRMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1886999-A2 | Bicyclic heteroaromatic compound | N.V. Organon (NL) | 2008-02-13 | — | — | EP | disclosed |
| CN-1247594-C | Bicyclic heteroaromatic compounds | OKZO NOBEL N V (NL) | 2006-03-29 | — | — | CN | disclosed |
| CN-1462273-A | Bicyclic heteroaromatic compounds | OKZO NOBEL N V (NL) | 2003-12-17 | — | — | CN | disclosed |