Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.84 |
| ▸ | P2RY12 | Q9H244 | 17/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3926740 | 0.91 | ALDH1A1 (1.00) | ALDH1A1P2RY12KDM4ENPSR1 | |
| SCHEMBL30999844 | 0.91 | ALDH1A1 (1.00) | ALDH1A1P2RY12KDM4ENPSR1 | |
| SCHEMBL4295294 | 0.84 | ALDH1A1 (0.73) | ALDH1A1P2RY12KDM4ENPSR1 | |
| SCHEMBL3874439 | 0.84 | ALDH1A1 (0.76) | ALDH1A1P2RY12KDM4E | |
| SCHEMBL30999840 | 0.84 | ALDH1A1 (0.76) | ALDH1A1P2RY12KDM4E | |
| SCHEMBL4425610 | 0.83 | ALDH1A1 (0.75) | ALDH1A1P2RY12KDM4ENPSR1 | |
| Hydrochloric Acid SCHEMBL4878714 | 0.83 | ALDH1A1 (0.74) | ALDH1A1P2RY12KDM4E | |
| SCHEMBL5066024 | 0.82 | ALDH1A1 (0.83) | ALDH1A1P2RY12KDM4ENPSR1 | |
| SCHEMBL5423936 | 0.81 | ALDH1A1 (0.56) | ALDH1A1P2RY12KDM4ENPSR1 | |
| SCHEMBL4005299 | 0.80 | ALDH1A1 (0.70) | ALDH1A1P2RY12KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041111-A1 | NEW PYRIDINE ANALOGUES | AstraZeneca AB (SE) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008002247-A1 | NEW PYRIDINE ANALOGUES | ASTRAZENECA AB (SE) | 2008-01-03 | — | — | WO | disclosed |