Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.55 |
| ▸ | DDO | Q99489 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GPR17 | Q13304 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17580228 | 0.82 | KDM4E (0.62) | DAODDOKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL5637951 | 0.82 | DAO (0.49) | DAODDOKDM4EHSD17B10TSHR | |
| SCHEMBL4436424 | 0.82 | KDM4E (0.48) | DAODDOKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL4437503 | 0.81 | MAPK1 (0.58) | DAODDOKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL4425807 | 0.77 | GPR17 (0.52) | GPR17 | |
| SCHEMBL1122187 | 0.76 | PTGDR2 (0.45) | DAODDOGPR17MAPTFFAR1 | |
| SCHEMBL3843996 | 0.75 | DAO (0.55) | DAODDOKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL31423115 | 0.74 | DAO (0.63) | DAODDOKDM4EHSD17B10TSHR | |
| SCHEMBL11192809 | 0.74 | DAO (0.50) | DAODDOKDM4EHSD17B10TSHR | |
| SCHEMBL31381369 | 0.74 | DAO (0.50) | DAODDOKDM4EHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125813-A2 | COMPOUNDS | Glaxo Group Limited (GB) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008116815-A2 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |