Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.51 |
| ▸ | DDO | Q99489 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5678790 | 0.84 | MAPK1 (0.61) | MAPK1NPSR1KDM4ETSHRDAO | |
| SCHEMBL30434363 | 0.84 | MAPK1 (0.61) | MAPK1NPSR1KDM4ETSHRDAO | |
| SCHEMBL28019335 | 0.82 | TSHR (0.57) | MAPK1NPSR1KDM4ETSHRDAO | |
| Bicarbonate SCHEMBL6993932 | 0.81 | MAPK1 (0.61) | MAPK1NPSR1KDM4ETSHRDAO | |
| SCHEMBL4425832 | 0.81 | DAO (0.55) | KDM4ETSHRDAODDOALDH1A1 | |
| SCHEMBL4428108 | 0.80 | KDM4E (0.60) | MAPK1NPSR1KDM4ETSHRALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL30355103 | 0.80 | MAPK1 (0.51) | MAPK1NPSR1KDM4ETSHRDAO | |
| SCHEMBL29417817 | 0.80 | MTNR1A (0.60) | MAPK1KDM4EDAOALDH1A1HPGD | |
| SCHEMBL606161 | 0.80 | MTNR1A (0.60) | MAPK1KDM4EDAOALDH1A1HPGD | |
| SCHEMBL7646960 | 0.79 | DAO (0.53) | MAPK1NPSR1KDM4ETSHRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125813-A2 | COMPOUNDS | Glaxo Group Limited (GB) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008116815-A2 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |
| US-5710139-A | Heterocyclic compounds | ASTRA AB (SE) | 1998-01-20 | — | — | US | disclosed |
| EP-0736032-A1 | HETEROCYCLIC COMPOUNDS | Astra Aktiebolag (SE) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017410-A1 | HETEROCYCLIC COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1995-06-29 | — | — | WO | disclosed |