Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 11/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4430524 | 0.82 | LMNA (0.43) | GPR17 | |
| SCHEMBL4426955 | 0.82 | DAO (0.56) | GPR17EGFRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL4425832 | 0.77 | DAO (0.55) | GPR17 | |
| SCHEMBL3841830 | 0.75 | GRIN1 (0.36) | GPR17CNR1GRIN2DGRIN3BGRIN1 | |
| Trifluoroacetic Acid SCHEMBL30355119 | 0.74 | NEK1 (0.39) | GPR17 | |
| Trifluoroacetic Acid SCHEMBL30355116 | 0.74 | NEK1 (0.39) | GPR17 | |
| SCHEMBL5047640 | 0.72 | MPO (0.36) | CNR1PARP1 | |
| Trifluoroacetic Acid SCHEMBL30355104 | 0.72 | TAAR1 (0.40) | NPSR1 | |
| SCHEMBL4715895 | 0.70 | FFAR1 (0.59) | GPR17NPSR1CNR1 | |
| SCHEMBL4159537 | 0.70 | MPO (0.43) | GPR17PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125813-A2 | COMPOUNDS | Glaxo Group Limited (GB) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008116815-A2 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |