Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 9/20 | 0.85 |
| ▸ | CA9 | Q16790 | 9/20 | 0.85 |
| ▸ | CA2 | P00918 | 8/20 | 0.85 |
| ▸ | CA1 | P00915 | 3/20 | 0.85 |
| ▸ | CA4 | P22748 | 2/20 | 0.85 |
| ▸ | CA7 | P43166 | 2/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.85 |
| ▸ | USP2 | O75604 | 1/20 | 0.85 |
| ▸ | LMNA | P02545 | 1/20 | 0.85 |
| ▸ | BCHE | P06276 | 1/20 | 0.85 |
| ▸ | CA6 | P23280 | 1/20 | 0.85 |
| ▸ | CA5A | P35218 | 1/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.85 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.85 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Saccharin SCHEMBL28045129 | 0.92 | CA12 (0.92) | CA12CA9CA2CA1CA4 | |
| Saccharin SCHEMBL27905604 | 0.92 | CA12 (0.92) | CA12CA9CA2CA1CA4 | |
| Saccharin SCHEMBL29109711 | 0.92 | CA12 (0.92) | CA12CA9CA2CA1CA4 | |
| Saccharin SCHEMBL29191365 | 0.92 | CA12 (1.00) | CA12CA9CA2CA1CA4 | |
| Saccharin SCHEMBL7073018 | 0.92 | CA12 (1.00) | CA12CA9CA2CA1CA4 | |
| Saccharin SCHEMBL29358404 | 0.92 | CA12 (1.00) | CA12CA9CA2CA1CA4 | |
| Saccharin SCHEMBL3816 | 0.92 | CA12 (1.00) | CA12CA9CA2CA1CA4 | |
| Saccharin SCHEMBL6033672 | 0.92 | CA12 (1.00) | CA12CA9CA2CA1CA4 | |
| Saccharin SCHEMBL588640 | 0.92 | CA12 (1.00) | CA12CA9CA2CA1CA4 | |
| Saccharin SCHEMBL4777123 | 0.92 | CA12 (1.00) | CA12CA9CA2CA1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357671-B2 | High affinity Siglec ligands | Paulson, James (US) | 2013-01-22 | — | — | US | disclosed |
| US-20090238837-A1 | High Affinity Siglec Ligands | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-09-24 | — | — | US | disclosed |
| EP-1951740-A2 | HIGH AFFINITY SIGLEC LIGANDS | Paulson, James (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007056525-A2 | HIGH AFFINITY SIGLEC LIGANDS | PAULSON JAMES (US) | 2007-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090238837-A1 | High Affinity Siglec Ligands | SIGLEC7, SIGLEC9, FCGR1A | CA12 1037/4885CA9 2015/4885CA2 3558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.