Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.90 |
| ▸ | POLB | P06746 | 1/20 | 0.90 |
| ▸ | CCR3 | P51677 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1711070 | 0.95 | SIGMAR1 (1.00) | SIGMAR1POLBCCR3KMT2AHTT | |
| SCHEMBL9149934 | 0.88 | SIGMAR1 (0.70) | SIGMAR1POLBCCR3KMT2AHTT | |
| SCHEMBL78043 | 0.87 | SIGMAR1 (0.79) | SIGMAR1POLBCCR3KMT2AHTT | |
| SCHEMBL9539677 | 0.87 | SIGMAR1 (0.79) | SIGMAR1POLBCCR3KMT2AHTT | |
| SCHEMBL8092982 | 0.85 | SIGMAR1 (0.85) | SIGMAR1CCR3KMT2AMEN1TP53 | |
| SCHEMBL20797123 | 0.85 | SIGMAR1 (0.81) | SIGMAR1POLBKMT2AHTT | |
| Sulfurous Acid SCHEMBL28001231 | 0.84 | SIGMAR1 (0.79) | SIGMAR1POLBKMT2AHTTMEN1 | |
| SCHEMBL7394691 | 0.84 | SIGMAR1 (0.68) | SIGMAR1POLBCCR3KMT2AMEN1 | |
| SCHEMBL7397638 | 0.84 | SIGMAR1 (0.68) | SIGMAR1POLBCCR3KMT2AMEN1 | |
| SCHEMBL11195592 | 0.84 | SIGMAR1 (0.68) | SIGMAR1POLBCCR3KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682538-A4 | BIARYL LINKED HYDROXAMATES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S BIO PTE LTD (SG) | 2009-05-27 | — | — | EP | claimed |
| US-20070167499-A1 | Biaryl linked hydroxamates: preparation and pharmaceutical applications | A*BIO PTE LTD. (SG) | 2007-07-19 | — | — | US | claimed |
| EP-1682538-A1 | BIARYL LINKED HYDROXAMATES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*Bio Pte Ltd (SG) | 2006-07-26 | — | — | EP | claimed |
| WO-2005040161-A1 | BIARYL LINKED HYDROXAMATES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2005-05-06 | — | — | WO | claimed |
| US-20150301461-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS AND PHTHALOCYANINE CRYSTAL | CANON KABUSHIKI KAISHA (JP) | 2015-10-22 | — | — | US | disclosed |
| US-20150301461-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS AND PHTHALOCYANINE CRYSTAL | CANON KABUSHIKI KAISHA (JP) | 2015-10-22 | — | — | US | disclosed |
| WO-2014092194-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS AND PHTHALOCYANINE CRYSTAL | CANON KABUSHIKI KAISHA (JP) | 2014-06-19 | — | — | WO | disclosed |
| EP-1682538-A4 | BIARYL LINKED HYDROXAMATES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S BIO PTE LTD (SG) | 2009-05-27 | — | — | EP | disclosed |
| US-20070167499-A1 | Biaryl linked hydroxamates: preparation and pharmaceutical applications | A*BIO PTE LTD. (SG) | 2007-07-19 | — | — | US | disclosed |
| EP-1682538-A1 | BIARYL LINKED HYDROXAMATES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*Bio Pte Ltd (SG) | 2006-07-26 | — | — | EP | disclosed |
| US-20050159470-A1 | Histone deacetylase inhibitors | SYRRX, INC. | 2005-07-21 | — | — | US | disclosed |
| WO-2005040161-A1 | BIARYL LINKED HYDROXAMATES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159470-A1 | Histone deacetylase inhibitors | HDAC5, HDAC1, HDAC10 | SIGMAR1 3591/4885POLB 2188/4885CCR3 3491/4885 |
| US-20070167499-A1 | Biaryl linked hydroxamates: preparation and pharmaceutical applications | HDAC1, HDAC11, HDAC2 | SIGMAR1 4425/4885POLB 525/4885CCR3 1991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.